GDF15 Antibody

• Catalog number
  A01583-1
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  GDF15
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human
• Analyses
  WB
• Immunogen
  E.coli-derived human GDF15 recombinant protein (Position: A195-I308). Human GDF15 shares 68.1% and 69.2% amino acid (aa) sequence identity with mouse and rat GDF15, respectively.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the GDF15 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The GDF15 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Growth/differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF15 is also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB. GDF15 mRNA is most abundant in the liver, with lower levels seen in some other tissues. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung.
• Related articles
  1. Hsiao E, Koniaris L, Zimmers-Koniaris T, Sebald S, Huynh T, Lee S (2000). "Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injury". Mol Cell Biol. 20 (10): 3742–3751. 2. Zimmers T, Jin X, Hsiao E, McGrath S, Esquela A, Koniaris L (2005). "Growth differentiation factor-15/macrophage inhibitory cytokine-1 induction after kidney and lung injury". Shock. 23 (6): 543–8.
• Gene Name
  GDF15
• Protein Name
  Growth/differentiation factor 15
• Gene Full Name
  growth differentiation factor 15
• Synonyms
  GDF15 | GDF-15 | GDF 15 | MIC1 | MIC-1 | MIC 1 | NAG1 | NAG-1 | NAG 1 | NRG1 | NRG-1 | NRG 1 | NSAID | PDF | PLAB | PTGF beta | PTGFB | Q99988
• Uniprot ID
  Q99988
• Entrez GeneID
  9518
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GDF15  
• Gene symbol
  GDF15
• Short name
  GDF15 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  growth differentiation factor 15 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  growth differentiation factor 15, GDF-15 and MIC-1 and MIC1 and NAG-1 and PDF and PLAB and PTGFB, GDF15 and IDBG-38078 and ENSG00000130513 and 9518, growth factor activity, Extracellular, Gdf15 and IDBG-163724 and ENSMUSG00000038508 and 23886, GDF15 and IDBG-641726 and ENSBTAG00000015618 and 618677

Gene info

• Identity
  HGNC:30142
• Gene
  GDF15
• Long gene name
  growth differentiation factor 15
• Synonyms
  • PLAB
  • MIC-1
  • PDF
  • MIC1
  • NAG-1
  • PTGFB
• Synonyms name
  • prostate differentiation factor
  • non-steroidal anti-inflammatory drug-activated gene-1
  • macrophage inhibitory cytokine-1
• GenBank acession
  • BC008962
• Locus
  19p13.11
• Discovery year
  2004-02-12
• Entrez gene record
  9518
• Pubmed identfication
  • 11895857
  • 9593718
• RefSeq identity
  • NM_004864
• Classification
  • Transforming growth factor beta superfamily
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000183360

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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