LY-2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC₅₀ of 2 nM and 10 nM, respectively. LY-2835219 inhibits the proliferation of Rb-positive tumor cells and demonstrates dose-dependent growth inhibition in ER+ breast cancer models.
Is it cell-permeable?
≥98% by HPLC
Is this a salt?
Protect from air and moisture
Maximum time for storage
White to off-white solid
DMSO (>50 mg/ml) or H₂O (>60 mg/ml)
For cells, cell lines and tissues in culture till half confluency.