Genistein-2’,3’,5’,6’-d4 (Major)
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Catalog number
G350010
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Price
Please ask
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Size
1 mg
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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
187960-08-3
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Chemical s molecular weight
274.26
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Chemical s main applications
Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol
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Chemical s category
Inhibitors, Tyrosine Kinase Inhibitors, Isotope Labelled Compounds
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Other name
5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d4; Baichanin A-d4; Bonistein-d4; 4',5,7-Trihydroxyisoflavone-d4; GeniVida-d4; Genisteol-d4; NSC 36586-d4; Prunetol-d4; Sophoricol-d4;
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Chemical s formula
C15H6D4O5
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Physical properties
Light Yellow to Yellow Solid
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Melting temperature
>275°C (dec.)
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Boiling temperature
No Data Available
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Chemical s soluble in
DMSO (Slightly), Methanol (Slightly)
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Stability conditions
No Data Available
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Storage
-20°C Freezer
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Gene target
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Short name
Genistein-2’,3’,5’,6’-d4 (Major)
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Alternative name
Genistein-2’,3’,5’,6’-d4 (Major)
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