Genistein-2’,3’,5’,6’-d4 (Major)

  • Catalog number
    G350010
  • Price
    Please ask
  • Size
    1 mg
  • Chemical available in other sizes
    Please inquire size and price
  • Stock availability
    In Stock
  • Cas number
    187960-08-3
  • Chemical s molecular weight
    274.26
  • Chemical s main applications
    Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol
  • Chemical s category
    Inhibitors, Tyrosine Kinase Inhibitors, Isotope Labelled Compounds
  • Other name
    5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d4; Baichanin A-d4; Bonistein-d4; 4',5,7-Trihydroxyisoflavone-d4; GeniVida-d4; Genisteol-d4; NSC 36586-d4; Prunetol-d4; Sophoricol-d4;
  • Chemical s formula
    C15H6D4O5
  • Physical properties
    Light Yellow to Yellow Solid
  • Melting temperature
    >275°C (dec.)
  • Boiling temperature
    No Data Available
  • Chemical s soluble in
    DMSO (Slightly), Methanol (Slightly)
  • Stability conditions
    No Data Available
  • Storage
    -20°C Freezer
  • Gene target
  • Short name
    Genistein-2’,3’,5’,6’-d4 (Major)
  • Alternative name
    Genistein-2’,3’,5’,6’-d4 (Major)
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