OVA Conjugated Transcription Termination Factor, RNA polymerase I (TTF1)
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Catalog number
CPG777Hu21
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Price
Please ask
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Size
50ug
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Source
Protein conjugation
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Predicted Molecular Mass KD
NA
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Accurate Molecular Mass KD
NA
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Organism species
Homo sapiens (Human)
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Item Name
Transcription Termination Factor, RNA polymerase I
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Alternative Names
RNA polymerase I termination factor
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Research Area
Signal transduction;
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Buffer Formulation
PBS, pH7.4.
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Traits
Freeze-dried powder
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Purity
> 90%
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Protein length
NA
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Tag
No tag
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Expression System
Protein Conjugation
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Application
Immunogen; SDS-PAGE; WB
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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Gene target
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Gene symbol
TTF1, NKX2-1
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Short name
OVA Conjugated Transcription Termination Factor, RNA polymerase I (TTF1)
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Technique
antibody Conjugates, RNAs are to store at -70 C
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Host
chemical synthesis
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Species
Homo sapiens (Human)
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Alternative name
OVA coupled Transcription Termination Factor, RNA polymerizing enzyme I (TTF1)
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Gene info
Gene info
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Identity
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Gene
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Long gene name
NK2 homeobox 1
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Synonyms gene
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Synonyms gene name
- benign chorea
- thyroid transcription factor 1
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Synonyms
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Locus
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Discovery year
1992-06-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NKL subclass homeoboxes and pseudogenes
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VEGA ID
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