Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Source 4 Hydroxynonenal conjugated to BSA
Specificity This is a highly specific antibody against 4 Hydroxynonenal.
Tested applications IF(IHC-P)
Clone Polyclonal antibody
Modification Site None
Synonyms 4-Hydroxy-2-Nonenal; 4Hydroxynonenal; 4-Hydroxynonenal; 4 HNE; 4HNE; 4-HNE; E-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA.
Purification Purified by Protein A.
Recommended dilutions IF(IHC-P)(1:50-200)
Background of the antigen Aldehydic products of lipid peroxidation, such as 4 hydroxynonenal (4 HNE), have been implicated in the etiology of pathological changes under oxidative stress as a key mediator of oxidative stress induced cell death. It is a stable product of lipid peroxidation, is proarrhythmic and may contribute to the cytotoxic effects of oxidative stress 4-HNE has been hypothesized to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion.
Concentration 1ug per 1ul
Target Antigen 4 Hydroxynonenal
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Cross-reactive species details 4-Hydroxynonenal