TGFB1 Antibody

• Catalog number
  F42108-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TGFB1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  IHC, IF, ELISA
• Recommended dilutions
  IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
• Notes
  Titration of the TGFB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This TGFB1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P01137
• Purity
  Antigen affinity
• Description
  TGFB1 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
• Immunogen
  A portion of amino acids 22-50 from the human protein was used as the immunogen for this TGFB1 antibody.
• Storage
  Aliquot the TGFB1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TGFB1  
• Gene symbol
  TGFB1
• Short name
  Anti-TGFB1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to TGFB1
• Alternative technique
  antibodies
• Alternative to gene target
  transforming growth factor, beta 1, CED and DPD1 and LAP and TGFB and TGFbeta, TGFB1 and IDBG-52846 and ENSG00000105329 and 7040, protein N-terminus binding, nuclei, Tgfb1 and IDBG-158292 and ENSMUSG00000002603 and 21803, TGFB1 and IDBG-638417 and ENSBTAG00000020457 and 282089

Gene info

• Identity
  HGNC:11766
• Gene
  TGFB1
• Long gene name
  transforming growth factor beta 1
• Synonyms gene
  • TGFB
  • DPD1
• Synonyms gene name
  • transforming growth factor, beta 1
• Synonyms
  • CED
  • TGFbeta
• Synonyms name
  • Camurati-Engelmann disease
  • prepro-transforming growth factor beta-1
  • Diaphyseal dysplasia 1, progressive
• GenBank acession
  • X02812
• Locus
  19q13.2
• Discovery year
  2001-06-22
• Entrez gene record
  7040
• Pubmed identfication
  • 10631145
  • 10843814
• Classification
  • Transforming growth factor beta family
• VEGA ID
  OTTHUMG00000182760

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products