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Caspase12 Antibody

Caspase12 Antibody is available 1 time from Boster labs

PA2103 | Caspase12 Antibody size: 0,1 mg | 365.60 USD

Catalog number PA2103
Supplier boster
Price 365.60 USD
Size 0,1 mg
MeSH Data
Tree numbers
  • E05.599.495
Clonality Polyclonal antibody
Analyses WB,IHC-P
Related articles 1. Fischer, H., Koenig, U., Eckhart, L., Tschachler, E. Human caspase 12 has acquired deleterious mutations. Biochem. Biophys. Res. Commun. 293: 722-726, 2002. 2. Saleh, M., Mathison, J. C., Wolinski, M. K., Bensinger, S. J., Fitzgerald, P., Droin, N., Ulevitch, R. J., Green D. R., Nicholson, D. W. Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Nature 440: 1064-1068, 2006. 3. Yeretssian, G., Doiron, K., Shao, W., Leavitt, B. R., Hayden, M. R., Nicholson, D. W., Saleh, M. Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection. Proc. Nat. Acad. Sci. 106: 9016-9020, 2009.
Raised in rabbit
Solubilization The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
Target antigen Caspase12
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human Caspase-12(71-84aa KIFREHLWNSKKQL).
Type of the antibody IgG polyclonal antibody
Uniprot ID Q6UXS9
Clone Polyclonal antibody
Protein Name Inactive caspase-12
Synonyms Apoptosis related cysteine protease antibody|CASP 12 antibody|CASP-12 antibody|casp12 antibody|CASP12P1 antibody|caspase 12(gene/pseudogene) antibody|caspase 12 pseudogene 1 antibody|Caspase 12 psuedogene 1 antibody|Caspase12 antibody|CASPC_HUMAN antibody|Inactive caspase-12 antibody|OTTHUMP00000207032 antibody|UNQ9415 antibody
Storage condtions Keep the Caspase12 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
Purification Immunogen affinity purified.
Background Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. The CASP12 gene was mapped to chromosome 11q22.3. Csp12L attenuates the inflammatory and innate immune response to endotoxins and in doing so may constitute a risk factor for developing sepsis. The estrogen-mediated inhibition of CSP12L expression is a built-in mechanism that has evolved to protect females from infection by favoring a more robust inflammatory response to pathogens, perhaps notably in childbirth.
Product form freeze-dried
Gene Name CASP12
Gene Full Name caspase 12(gene/pseudogene)
Product configuration Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reacts with species: Human. No cross reactivity with other proteins.
Tips The Caspase12 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
Properties If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetCaspase12
Short name Caspase12 Antibody
Technique Antibody
Alternative name Caspase12 (Antibody to)
Alternative technique antibodies
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