Leukemia BCR-ABL Fusion Gene Typing Real Time RT-PCR Kit

• Catalog number
  MBS598267
• Price
  Please ask
• Size
  25 Tests/Kit (Instr, I, II Recommended)

• Other size
  please contact us to order other different size
• Description
  Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.
• Group
  PCR, polymerase chain reaction, RT-PCR mixes
• About
  TAQ or Pfu or Pfx or other enzymes are used for polycmerase chain reaction and have different specificity. The mores specific the lower the yield.
• Properties
  Thermocyclers can be callibrated for identical ramping curves to obtain a more accurate PCR.

• Gene target
  Leukemia   BCR-ABL   Gene   Typing   Real   Time   Kit  
• Gene symbol
  ABL1, BCRP1, MTTP, BCRP2, BCRP4, BCR
• Short name
  Leukemia BCR-ABL Typing Real Time RT-PCR Kit
• Technique
  RT-PCR, PCR, The polymerase chain reaction (PCR) amplifies the DNA in your sample. For real time PCR the cycle threshold Ct values willneed to be set before the experiment. Than the RT-PCR starts from RNA and real time PCR quantitates the cDNA so the RNA in the sample on given time of the experiment.
• Alternative name
  Leukemia BCR-ABL Fusion Gene Typing Real Time Reverse transcription PCR test kit reagent
• Alternative technique
  rtpcrkits, kits, dna-amplification
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
• Virus
  leukemia

Gene info

• Identity
  HGNC:76
• Gene
  ABL1
• Long gene name
  ABL proto-oncogene 1, non-receptor tyrosine kinase
• Synonyms gene
  • ABL
• Synonyms gene name
  • v-abl Abelson murine leukemia viral oncogene homolog 1
  • c-abl oncogene 1, receptor tyrosine kinase
  • c-abl oncogene 1, non-receptor tyrosine kinase
• Synonyms
  • JTK7
  • c-ABL
  • p150
• GenBank acession
  • M14752
• Locus
  9q34.12
• Discovery year
  1986-01-01
• Entrez gene record
  25
• Pubmed identfication
  • 1857987
  • 12626632
• RefSeq identity
  • NM_007313
• Classification
  • Abl family tyrosine kinases
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000020813
• Locus Specific Databases
  • LRG_769

Gene info

• Identity
  HGNC:39073
• Gene
  BCRP1
• Long gene name
  BCR pseudogene 1
• Synonyms gene name
  • breakpoint cluster region pseudogene 1
• Synonyms
  • BCR-1
• Locus
  22q11.23
• Discovery year
  2010-09-30
• Entrez gene record
  644079
• Pubmed identfication
  • 3267213
• RefSeq identity
  • NG_009423
• VEGA ID
  OTTHUMG00000150768

Gene info

• Identity
  HGNC:7467
• Gene
  MTTP
• Long gene name
  microsomal triglyceride transfer protein
• Synonyms gene
  • MTP
• Synonyms gene name
  • microsomal triglyceride transfer protein (large polypeptide, 88kD)
  • microsomal triglyceride transfer protein (large polypeptide, 88kDa)
• Synonyms
  • ABL
• Locus
  4q23
• Discovery year
  1994-12-07
• Entrez gene record
  4547
• Pubmed identfication
  • 8111381
• RefSeq identity
  • NM_000253
• VEGA ID
  OTTHUMG00000131023

Gene info

• Identity
  HGNC:1015
• Gene
  BCRP2
• Long gene name
  BCR pseudogene 2
• Synonyms gene
  • BCR2
  • BCRL2
• Synonyms gene name
  • breakpoint cluster region-like 2
  • breakpoint cluster region pseudogene 2
• Synonyms
  • BCR-2
• Locus
  22q11.21
• Discovery year
  2001-06-22
• Entrez gene record
  400892
• Pubmed identfication
  • 3267213
• RefSeq identity
  • NG_007131
• VEGA ID
  OTTHUMG00000150627

Gene info

• Identity
  HGNC:1017
• Gene
  BCRP4
• Long gene name
  BCR pseudogene 4
• Synonyms gene
  • BCR4
  • BCRL4
• Synonyms gene name
  • breakpoint cluster region-like 4
  • breakpoint cluster region pseudogene 4
• Synonyms
  • BCR-4
• GenBank acession
  • D87002
• Locus
  22q11.22
• Discovery year
  2001-06-22
• Entrez gene record
  616
• Pubmed identfication
  • 9074928
• RefSeq identity
  • NG_000002
• VEGA ID
  OTTHUMG00000151175

Gene info

• Identity
  HGNC:1014
• Gene
  BCR
• Long gene name
  BCR activator of RhoGEF and GTPase
• Synonyms gene
  • D22S11
  • BCR1
• Synonyms gene name
  • breakpoint cluster region
  • BCR, RhoGEF and GTPase activating protein
• Synonyms
  • D22S662
  • CML
  • PHL
  • ALL
• Locus
  22q11.23
• Discovery year
  1986-01-01
• Entrez gene record
  613
• Pubmed identfication
  • 1657398
  • 18070886
• RefSeq identity
  • NM_004327
• Classification
  • C2 domain containing
  • My-T-BRC complex
  • Dbl family Rho GEFs
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000150655
• Locus Specific Databases
  • LRG_1112

MeSH Data

• Name
  Nucleic Acid Amplification Techniques
• Concept
  Scope note: Laboratory techniques that involve the in-vitro synthesis of many copies of DNA or RNA from one original template.
• Tree numbers
  • E05.393.620
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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