Kallikrein 1 Antibody

• Catalog number
  PA1625
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Kallikrein 1
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human
• Analyses
  WB,IHC-P
• Immunogen
  A synthetic peptide corresponding to a sequence in the middle region of human Kallikrein 1(182-197aa NDECKKAHVQKVTDFM).
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Kallikrein 1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Kallikrein 1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  KLK1(KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
• Related articles
  1. Azizi, M., Boutouyrie, P., Bissery, A., Agharazii, M., Verbeke, F., Stern, N., Bura-Riviere, A., Laurent, S., Alhenc-Gelas, F., Jeunemaitre, X. Arterial and renal consequences of partial genetic deficiency in tissue kallikrein activity in humans. J. Clin. Invest. 115: 780-787, 2005. 2. Baker, A. R., Shine, J. Human kidney kallikrein: cDNA cloning and sequence analysis. DNA 4: 445-450, 1985. 3. Clements J, Hooper J, Dong Y, Harvey T (2001). "The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions".
• Gene Name
  KLK1
• Protein Name
  Kallikrein-1
• Gene Full Name
  kallikrein 1
• Synonyms
  Glandular kallikrein 1 antibody|hK 1 antibody|hK1 antibody|Kallikrein serine protease 1 antibody|Kallikrein-1 antibody|Kidney/pancreas/salivary gland kallikrein antibody|Klk 6 antibody|KLK1 antibody|KLK1_HUMAN antibody|Klk6 antibody|KLKR antibody|Tissue kallikrein antibody
• Uniprot ID
  P06870
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Kallikrein  
• Gene symbol
  KLK1, KLKP1, KLKB1
• Short name
  Kallikrein 1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Kallikrein 1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6357
• Gene
  KLK1
• Long gene name
  kallikrein 1
• Synonyms gene name
  • kallikrein 1, renal/pancreas/salivary
• Synonyms
  • Klk6
• GenBank acession
  • L10038
• Locus
  19q13.33
• Discovery year
  1988-06-27
• Entrez gene record
  3816
• Pubmed identfication
  • 1684954
  • 16800724
  • 16800723
• RefSeq identity
  • NM_002257
• Classification
  • Kallikreins
• VEGA ID
  OTTHUMG00000182876

Gene info

• Identity
  HGNC:21260
• Gene
  KLKP1
• Long gene name
  kallikrein pseudogene 1
• Synonyms
  • YKLK1
  • PsiKLK1
  • KLK31P
• Synonyms name
  • kallikrein 31 pseudogene
• GenBank acession
  • AY302756
• Locus
  19q13.33
• Discovery year
  2005-08-04
• Entrez gene record
  606293
• Pubmed identfication
  • 15498522
  • 16541416
  • 18196551
• RefSeq identity
  • NG_005220
• VEGA ID
  OTTHUMG00000183118

Gene info

• Identity
  HGNC:6371
• Gene
  KLKB1
• Long gene name
  kallikrein B1
• Synonyms gene
  • KLK3
• Synonyms gene name
  • kallikrein B, plasma (Fletcher factor) 1
• Synonyms name
  • Fletcher factor
• GenBank acession
  • M13143
• Locus
  4q35.2
• Discovery year
  1999-04-23
• Entrez gene record
  3818
• Pubmed identfication
  • 9535413
  • 3521732
• RefSeq identity
  • NM_000892
• Classification
  • Kallikreins
• VEGA ID
  OTTHUMG00000150347
• Locus Specific Databases
  • LRG_565

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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