LDLR Antibody

• Catalog number
  3839-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  LDLR
• Target Alternative Name
  FH , FHC , LDL receptor , LDLR , LDLR precursor
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat, bovine, hamster
• Immunogen Sequence
  Synthetic peptide corresponding to residues surrounding amino acids 850 of human LDLR
• Accession
  P01130
• Gene Id
  3949
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  30 µg (0.5 mg/ml) affinity purified rabbit anti-LDLR polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes mature LDLR (160 kDa), LDLR precursor (120 kDa) and LDLR monomer (~50 kDa).
• Description
  Low density lipoprotein receptors (LDLR) are cell surface glycoproteins that regulate LDL cholesterol by scavenging LDL from the blood. LDLR is characterized by a cluster of cysteine-rich class A repeats, EGF-like repeats, the O-linked sμgars domain and six YWTD or class B repeats. Mutations in the LDLR gene cause autosomal dominant disease such as familial hypercholesterolemia (FH) and atherosclerosis.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  LDLR  
• Gene symbol
  LDLR, LDLR-AS1
• Short name
  LDLR Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  low density lipoprotein receptor (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  low density lipoprotein receptor, FH and FHC and LDLCQ2, LDLR and IDBG-28808 and ENSG00000130164 and 3949, very-low-density lipoprotein particle receptor activity, Cell surfaces, Ldlr and IDBG-141358 and ENSMUSG00000032193 and 16835, LDLR and IDBG-643476 and ENSBTAG00000012314 and 281276

Gene info

• Identity
  HGNC:6547
• Gene
  LDLR
• Long gene name
  low density lipoprotein receptor
• Synonyms
  • LDLCQ2
• Synonyms name
  • familial hypercholesterolemia
• GenBank acession
  • AY114155
• Locus
  19p13.2
• Discovery year
  1986-01-01
• Entrez gene record
  3949
• Classification
  • Low density lipoprotein receptors
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000171935
• Locus Specific Databases
  • UCL LDLR-LOVD, British Heart Foundation variant database
  • UMD Locus Specific Databases
  • LRG_274

Gene info

• Identity
  HGNC:54407
• Gene
  LDLR-AS1
• Long gene name
  LDLR antisense RNA 1
• Synonyms
  • BM450697
• Locus
  19p13.2
• Discovery year
  2019-08-08
• Entrez gene record
  115271120
• Pubmed identfication
  • 31279228
• RefSeq identity
  • NR_163945
• Classification
  • Antisense RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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