anti- PAICS antibody

• Catalog number
  FNab06115
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
• Immunogen
  phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
• Synonyms
  ADE2, AIRC, PAIS
• Calculated MW
  45 kDa
• Uniprot ID
  P22234
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, IHC, WB
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
• Image1
  Immunohistochemistry of paraffin-embedded human liver using FNab06115(PAICS antibody) at dilution of 1:50
• Image4
  Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06115(PAICS antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PAICS  
• Gene symbol
  PAICS
• Short name
  anti- PAICS antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- PAICS (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8587
• Gene
  PAICS
• Long gene name
  phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
• Synonyms gene
  • PAIS
• Synonyms gene name
  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
• Synonyms
  • ADE2H1
  • AIRC
• GenBank acession
  • X53793
• Locus
  4q12
• Discovery year
  1991-03-11
• Entrez gene record
  10606
• Pubmed identfication
  • 2253271
  • 8106516
• RefSeq identity
  • NM_006452
• Classification
  • Purinosome
• VEGA ID
  OTTHUMG00000160957

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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