Transferrin (HOLO), Human Plasma
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Catalog number
7542-100
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Price
Please ask
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Size
100 mg
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Synonyms
Transferrin, Siderophilin, TF, DKFZp781D0156, PRO1557, PRO2086
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Alternative_names
Transferrin, Siderophilin, TF, DKFZp781D0156, PRO1557, PRO2086
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Description
The specific iron-binding protein in plasma.
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Recombinant
No
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Source
Human Plasma
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Purity by SDS PAGE
≥95%
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Assay
SDS-PAGE
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Molecular Weight
80.0 kDa
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Storage Temp
-20°C
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Shipping
Gel Pack
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Shelf Life
12 months
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Appearance
Lyophilized
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Physical form description
Lyophilized from 20 mM Na phosphate, pH 7.4 and 150 mM NaCI.
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Background Information
Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and in prevention of iron loss via the kidney. Stored in bone marrow as TF-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypo-proteinemias and nephritic syndrome; increases are found in pregnancy, iron-deficiency anemias and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important factor used in defined culture media.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Short name
Transferrin (HOLO), Plasma
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Species
Human, Humans
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Alternative name
Transferrin (HOLO), H. sapiens Plasma
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