Recombinant Human FRZB / sFRP-3 Protein (His tag) 50µg
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Catalog number
PKSH031646-50µg
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Price
Please ask
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Size
50µg
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Synonym
FRE;FRITZ;FRP-3;FRZB-1;FRZB-PEN;FRZB1;FZRB;hFIZ;OS1;SFRP3;SRFP3
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Activity
NA
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Sequence
Ala32-Asn325
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Fusion tag
C-His
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Accession
NP_001454.2
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Expressed Host
HEK293 Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
＞85 % as determined by SDS-PAGE
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Endotoxin
＜1.0 EU per µg as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
34.5 kDa
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AP Mol Mass
41 kDa
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Formulation
Lyophilized from sterile PBS, pH 7.4
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Reconstitution
Please refer to it for detailed information.
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Background
FRZB also known as sFRP-3, is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. FRZB is widely expressed in adult mammalian tissues. In the Xenopus gastrula, FRZB is regulated as a typical Spemann organizer component. FRZB also functions as a competitor for the cell-surface G-protein receptor Frizzled. It is espically important in embryonic development. Defects in FRZB gene can cause female-specific osteoarthritis (OA) susceptibility. FRZB may serve an important role in determining hip shape and may modify the relationship between hip shape and OA.
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
FRZB, SFRP4
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Short name
Recombinant FRZB / sFRP-3 Protein (His tag) 50µg
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
His
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Species
Human, Humans
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Alternative name
Rec. H. sapiens frizzled-related protein / sFRP-3 Protein (histidine detection labelled) 50µg
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Alternative technique
rec
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Alternative to gene target
frizzled-related protein, FRE and FRITZ and FRP-3 and FRZB-1 and FRZB-PEN and FRZB1 and FZRB and hFIZ and OS1 and SFRP3 and SRFP3, FRZB and IDBG-76878 and ENSG00000162998 and 2487, Wnt-activated receptor activity, Extracellular, Frzb and IDBG-183775 and ENSMUSG00000027004 and 20378, FRZB and IDBG-639871 and ENSBTAG00000010977 and 281170
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Gene info
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Identity
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Gene
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Long gene name
frizzled related protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1998-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Secreted frizzled-related proteins
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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