Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Source KLH conjugated synthetic peptide derived from Transmembrane protein gp41
Specificity This is a highly specific antibody against HIV gp41.
Tested applications IF(IHC-P)
Clone Polyclonal antibody
Modification Site None
Synonyms HIV1 gp41; HIV-1 gp41; HIV1gp41; HIVgp41; Transmembrane protein gp41; Glycoprotein 41; Human Immunodeficiency Virus 1; HIV1 ENV gp160; HIV1 gp160; HIV1gp160; HIV-1 gp160; env; Env polyprotein; Envelope glycoprotein gp160; Glycoprotein 41; gp41; HIV1; HIV1 clade a; HIV1/Clade A; SU; Surface protein; Human Immunodeficiency Virus Type 1 TM; Transmembrane protein; ENV_HV1MV.
Purification Purified by Protein A.
Recommended dilutions IF(IHC-P)(1:50-200)
Background of the antigen gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
Concentration 1ug per 1ul
Target Antigen HIV gp41
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Cross-reactive species details HIV