Anti-CD140b Rabbit Monoclonal Antibody

• Catalog number
  A1604-50
• Price
  Please ask
• Size
  50 µl

• Antibody Target
  CD140b
• Target Alternative Name
  PDGFRB; PDGFR; PDGFR1; Platelet-derived growth factor receptor beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1
• Antibody Type
  Monoclonal
• Clone
  RM303
• Species Reactivities
  Human
• Immunogen Sequence
  A peptide corresponding to the C-terminus of human CD140b
• Accession
  P09619
• Gene Id
  5159
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
• Purification
  Affinity purified
• Application
  WB, IHC
• Positive Control
  WB: human brain tissue lysate, IHC: human kidney tissue section
• Application And Usages
  WB: 1:250-1:500, IHC: 1:500-1:1000
• Description
  Platelet-derived growth factor (PDGF) refers to a family of disulphide-bonded dimeric isoforms that are important for growth and survival, and which function in several types of connective tissue cell. There are four members of the platelet-derived growth factor (PDGF) family: PDGF-A, PDGF-B, PDGF-C and PDGF-D (spinal cord-derived growth factor-B or iris-expressed growth factor). Their biological effects are mediated via two tyrosine kinase receptors, PDGFR-α and PDGFR-β. PDGF-mediated signaling is critical for development of many organ systems. PDGF-D has a two-domain structure similar to PDGF-C and is secreted as a disulphide-linked homodimer, PDGF-DD. Upon limited proteolysis, PDGF-DD is activated and becomes a specific agonistic ligand for PDGFR-β. PDGF-D is expressed in fibroblastic adventitial cells, cultured endothelial cells and in a variety of tumor cell lines.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rabbits are used for polyclonal antibody production by Biovision. Rabbit antibodies are very stable and can be stored for several days at room temperature. Biovision adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  CD140b   Monoclonal  
• Short name
  Anti-CD140b Rabbit Monoclonal Antibody
• Technique
  Antibody, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Rabbit, Rabbits
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toCD140b production species: rabbit monoclonal (antibody to-)
• Alternative technique
  antibodies, rabbit-anti

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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