Pan Caspase Inhibitor (Z-VAD(OMe)-FMK)
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Catalog numberAB-001
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PricePlease ask
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Size5 mg
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DescriptionHuman and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolPSMB7, PLA2G4F, HLA-Z, ZNF276
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Short namePan Caspase Inhibitor (Z-VAD(OMe)-FMK)
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Alternative namePan caspase suppressor (Z-VAD(OMe)-FMK)
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Gene info
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Identity
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Gene
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Long gene nameproteasome 20S subunit beta 7
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Synonyms gene name
- proteasome (prosome, macropain) subunit, beta type, 7
- proteasome subunit beta 7
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-11-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Proteasome
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephospholipase A2 group IVF
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Synonyms gene name
- phospholipase A2, group IVF
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Synonyms
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Locus
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Discovery year2005-11-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C2 domain containing phospholipases
- Phospholipases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class I, Z (pseudogene)
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Synonyms
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Locus
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Discovery year2002-10-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namezinc finger protein 276
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Synonyms gene
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Synonyms gene name
- zinc finger protein 276 homolog (mouse)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-11-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers C2H2-type
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
- E05.599.495