Human IGF-BP2[IGF-BP2]

Products_type

Recombinant Protein
Products_gene_name

[IGF-BP2]
Reactivity

Species Reactivity: HumanCross Reactivity: Mouse
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description

IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.

Identity

HGNC:10874
Gene

SIGLEC5
Long gene name

sialic acid binding Ig like lectin 5
Synonyms gene
- CD33L2
Synonyms gene name
- sialic acid binding Ig-like lectin 5
Synonyms
- OB-BP2
- SIGLEC-5
- CD170
GenBank acession
- U71383
Locus

19q13.41
Discovery year

1998-12-16
Entrez gene record

8778
Pubmed identfication
- 10343116
RefSeq identity
- NM_003830
Classification
- CD molecules
- Sialic acid binding Ig like lectins
- V-set domain containing
VEGA ID

OTTHUMG00000165510