BCRP (ABCG2) Antibody

• Catalog number
  6971-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  BCRP (ABCG2)
• Target Alternative Name
  Breast Cancer Resistance Protein, BCRP1, ATP-binding cassette sub-family G member 2, ATP binding cassette sub family G (WHITE) member 2, ABCG2, Mitoxantrone resistance associated protein, MXR, MXR1
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Synthetic peptide corresponding to amino acids around position 160 of human ABCG2
• Accession
  Q9UNQ0
• Gene Id
  9429
• Appearance
  Solid
• Form
  Lyophilized
• Formulation
  Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3, 0.05 mg Thimerosal
• Purification
  Immunogen affinity purified antibody
• Application
  Western Blot
• Positive Control
  WB: HeLa cells, SW620 cells, MCF-7 cells, SKOV cells, Jurkat cell
• Application And Usages
  WB: 1:1000-1:5000 of 0.5 mg/ml stock
• Description
  BCRP, also called ABCG2, is encoded by the ABCG2 gene. BCRP is a well-characterized ABC-transporter (which limits uptake or mediates efflux of a wide variety of drugs, carcinogens, dietary toxins across cellular membranes). It is an ATP-dependent pump with broad substrate specificity. Significant expression has been observed in the placenta and it has been shown to have a role in protecting the fetus from xenobiotics in the maternal circulation. It plays protective roles in blocking absorption at the apical membrane of the intestine, and at the blood-testis barrier, the blood–brain barrier and the membranes of hematopoietic progenitor and other stem cells. At the apical membranes of the liver and kidney, it enhances excretion of xenobiotics. In the lactating mammary gland, it has a role on excreting vitamins such as riboflavin and biotin into milk.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The vial should be centrifuged to collect the lyophilized solid before reconstituting
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BCRP   ABCG2  
• Gene symbol
  ABCG2
• Short name
  BCRP (ABCG2) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  BCRP (ABCG2) (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:74
• Gene
  ABCG2
• Long gene name
  ATP binding cassette subfamily G member 2 (Junior blood group)
• Synonyms gene name
  • ATP-binding cassette, sub-family G (WHITE), member 2
  • ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
• Synonyms
  • EST157481
  • MXR
  • BCRP
  • ABCP
  • CD338
• GenBank acession
  • AF103796
• Locus
  4q22.1
• Discovery year
  1999-10-26
• Entrez gene record
  9429
• Pubmed identfication
  • 8894702
  • 9861027
• RefSeq identity
  • NM_004827
• Classification
  • ATP binding cassette subfamily G
  • Blood group antigens
  • CD molecules
• VEGA ID
  OTTHUMG00000130601
• Locus Specific Databases
  • LRG_823

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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