anti-GRM5 Antibody

• Catalog number
  48-372
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  Group I of the Metabotropic Glutamate Receptors includes GRM1 and GRM5, receptors that have been shown to activate phospholipase C. Alternative splice variants of GRM5 have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain. GRM5 is involved in inflammatory mechanical hyperalgesia and potentially in schizophrenia
• Gene names
  GRM5, GPRC1E, MGLUR5, Mglur5b, MGlu5
• Antibodie s label
  unlabelled serum
• Purity
  Immunoaffinity Chromatography
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Antigen
  GRM5 antibody was made against a peptide located in the N-Terminal extracellular domain of GRM5 (Human).
• Immuno application
  immuno-histo-chemistry
• Antibody advice
  GRM5 antibody can be used in Western Blot starting at 1:100, and immunohistochemistry starting at 1:100.
• Suspention pH azide
  PBS, 0.1% sodium azide.
• Keep at
  GRM5 antibody should be stored long term (months) at -80 grades C and short term (days) at 4 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Bat, Gibbon, Bovine, Chicken, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
• Omim nr
  1709020
• Ncbi nr
  P41594
• Vial with antibody
  in solution
• NCBI GENE nr
  2915
• GENE symbol
  GRM5
• Antigene name
  glutamate receptor, metabotropic 5
• Source
  Homo sapiens
• Protein nr
  P41594
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GRM5  
• Gene symbol
  GRM5-AS1, GRM5
• Short name
  anti-GRM5 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toGRM5 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:40265
• Gene
  GRM5-AS1
• Long gene name
  GRM5 antisense RNA 1
• Synonyms gene name
  • GRM5 antisense RNA 1 (non-protein coding)
• Locus
  11q14.2
• Discovery year
  2011-11-18
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000167293

Gene info

• Identity
  HGNC:4597
• Gene
  GRM5
• Long gene name
  glutamate metabotropic receptor 5
• Synonyms gene name
  • glutamate receptor, metabotropic 5
• Synonyms
  • MGLUR5
  • GPRC1E
  • mGlu5
  • PPP1R86
• Synonyms name
  • protein phosphatase 1, regulatory subunit 86
• GenBank acession
  • D28538
• Locus
  11q14.2-q14.3
• Discovery year
  1993-10-22
• Entrez gene record
  2915
• Pubmed identfication
  • 7908515
• RefSeq identity
  • NM_000842
• Classification
  • Glutamate metabotropic receptors
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000134306

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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