CXCL2, human recombinant

• Catalog number
  7306-100
• Price
  Please ask
• Size
  100 ug

• Synonyms
  C-X-C motif chemokines 2, MIP2-alpha, Gro-beta, CINC-2a, GRO2, GROb, MIP2, MIP2A, SCYB2
• Alternative_names
  C-X-C motif chemokines 2, MIP2-alpha, Gro-beta, CINC-2a, GRO2, GROb, MIP2, MIP2A, SCYB2
• Description
  Suppresses hematopoietic progenitor cell proliferation
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per 1 microgram of protein
• Molecular Weight
  10.1 kDa (94 aa, 35-107 aa + His tag), confirmed by MALDI-TOF.
• Storage Temp
  -80°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Concentration
  1 mg/ml
• Appearance
  Liquid
• Physical form description
  1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0).
• Background Information
  CXCL2 is a small cytokine belonging to the CXC chemokine family that is also known as Chemokine (C-X-C motif) ligand 2, and macrophage inflammatory protein 2-alpha (MIP2-alpha). CXCL2 is secreted by activated monocytes, neutrophils and macrophages and expressed at sites of inflammation. CXCL2 is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells and suppresses hematopoietic progenitor cell proliferation. Recombinant human CXCL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
• Amino acid sequence
  MGSSHHHHHH SSGLVPRGSH MAPLATELRC QCLQTLQGIH LKNIQSVKVK SPGPHCAQTE VIATLKNGQK ACLNPASPMV KKIIEKMLKN GKSN
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CXCL2  
• Gene symbol
  CXCL2
• Short name
  CXCL2, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  chemokine (C-X-C motif) ligand 2, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  chemokine (C-X-C motif) ligand 2, CINC-2a and GRO2 and GROb and MGSA-b and MIP-2a and MIP2 and MIP2A and SCYB2, CXCL2 and IDBG-24257 and ENSG00000081041 and 2920, chemokine activity, Extracellular

Gene info

• Identity
  HGNC:4603
• Gene
  CXCL2
• Long gene name
  C-X-C motif chemokine ligand 2
• Synonyms gene
  • GRO2
• Synonyms gene name
  • GRO2 oncogene
  • chemokine (C-X-C motif) ligand 2
• Synonyms
  • SCYB2
  • GROb
  • MIP-2a
  • MGSA-b
  • CINC-2a
• GenBank acession
  • M36820
• Locus
  4q13.3
• Discovery year
  1991-05-21
• Entrez gene record
  2920
• Pubmed identfication
  • 2217207
• RefSeq identity
  • NM_002089
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000160865

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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