Human Recombinant FKBP6
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Catalog number6344-50
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PricePlease ask
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Size50 ug
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SynonymsHuman Recombinant FKBP6
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Alternative_namesFK506 binding protein 6, FKBP36, PPIase FKBP6.
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DescriptionAn immunophilin family protein functioning as a protein folding chaperone
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RecombinantYes
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SourceE. Coli
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Purity by SDS PAGE≥95%
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AssaySDS-PAGE
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Biological activitySpecific activity is > 190 nmoles/min/mg.
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Unit DefinitionSpecific activity is defined as the amount of enzyme that cleaves 1 µmole of suc-AAFP-pNA per minute at 25°C in Tris HCl pH 8.0 using chymotrypsin.
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Molecular Weight39.3 kDa
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Storage Temp-20°C
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Shippinggel pack
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Shelf Life12 months
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Concentration0.5 mg/ml
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AppearanceLiquid
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Physical form description0.5 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 40% glycerol, 1 mM EDTA and 50 mM NaCl.
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Background InformationFKBP6 is part of the immunophilin protein family, and is involved in immunoregulation and basic cellular functions involving protein folding and trafficking. FKBP6 is widely expressed in all tissues, FKBP6 is present at utmost levels in testis, liver, kidney, skeletal muscle and heart. Deletion of FKBP6 contributes to hypercalcemia and growth delay in Williams-Beuren syndrome.
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Amino acid sequenceMGSSHHHHHH SSGLVPRGSH MGGSALNQGV LEGDDAPGQS LYERLSQRML DISGDRGVLK DVIREGAGDL VAPDASVLVK YSGYLEHMDR PFDSNYFRKT PRLMKLGEDI TLWGMELGLL SMRRGELARF LFKPNYAYGT LGCPPLIPPN TTVLFEIELL DFLDCAESDK FCALSAEQQD QFPLQKVLKV AATEREFGNY LFRQNRFYDA KVRYKRALLL LRRRSAPPEE QHLVEAAKLP VLLNLSFTYL KLDRPTIALC YGEQALIIDQ KNAKALFRCG QACLLLTEYQ KARDFLVRAQ KEQPFNHDIN NELKKLASCY RDYVDKEKEM WHRMFAPCGD GSTAGES
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolFKBP6, FKBP10
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Short nameRecombinant FKBP6
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameH. sapiens Rec. FK506 binding protein 6, 36kDa
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Alternative techniquerec
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Alternative to gene targetFK506 binding protein 6, 36kDa, FKBP36, FKBP6 and IDBG-19838 and ENSG00000077800 and 8468, Hsp90 protein binding, Cytoplasm, Fkbp6 and IDBG-203707 and ENSMUSG00000040013 and 94244, FKBP6 and IDBG-640067 and ENSBTAG00000002253 and 537921
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Gene info
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Identity
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Gene
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Long gene nameFKBP prolyl isomerase family member 6 (inactive)
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Synonyms gene name
- FK506-binding protein 6 (36kD)
- FK506 binding protein 6, 36kDa
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-12-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- FKBP prolyl isomerases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameFKBP prolyl isomerase 10
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Synonyms gene name
- FK506 binding protein 10 (65 kDa)
- FK506 binding protein 10, 65 kDa
- FK506 binding protein 10
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-03-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EF-hand domain containing
- FKBP prolyl isomerases
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data