CD177 monoclonal antibody

• Catalog number
  1A-314-T100
• Price
  Please ask
• Size
  100 assays

• Long name
  Mouse Monoclonal Antibody against Human CD177, Clone: MEM-166
• Antigen
  CD177
• Species reactivity
  Non-Human (Homo sapiens) Primates, Human (Homo sapiens)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  MEM-166
• Applications
  FC, IP, WB
• Immunogen
  Human granulocytes
• Format conjugation
  APC
• Specificity
  The antibody MEM-166 reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes. _x000D_ HLDA VI; WS Code M M17_x000D_ HLDA VI; WS Code BP 309 _x000D_
• Research area
  CD Antigens & MHC (Veterinary), CD and Related Antigens (Human)
• Storage buffer
  The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
• Shipping and storage
  Mouse Monoclonal Antibody against Human CD177, Clone: MEM-166 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by affinity chromatography
• Datasheet
• References
  *Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997).
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  CD177   monoclonal  
• Gene symbol
  CD177
• Short name
  Anti-CD177 Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG1
• Alternative name
  Mouse Monoclonal to CD177
• Alternative technique
  antibodies
• Alternative to gene target
  CD177 molecule, CD177 and IDBG-55103 and ENSG00000204936 and 57126, Plasma membranes, Cd177 and IDBG-155436 and ENSMUSG00000052212 and 68891, BT.78171 and IDBG-638968 and ENSBTAG00000002976 and 616350

Gene info

• Identity
  HGNC:30072
• Gene
  CD177
• Long gene name
  CD177 molecule
• Synonyms gene name
  • CD177 antigen
• Synonyms
  • PRV1
  • HNA2A
  • NB1
• Synonyms name
  • polycythemia rubra vera 1
• GenBank acession
  • AF146747
• Locus
  19q13.31
• Discovery year
  2005-08-12
• Entrez gene record
  57126
• Pubmed identfication
  • 10753836
  • 5552408
• RefSeq identity
  • NM_020406
• Classification
  • CD molecules
  • LY6/PLAUR domain containing
• VEGA ID
  OTTHUMG00000185320

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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