anti-Vinculin Antibody [7E10]

• Catalog number
  PM-7811
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5).
• Gene names
  CMD1W, CMH15, Metavinculin, MVCL
• Antibodie s label
  unlabelled serum
• Purity
  Vinculin antibody is purified via Protein A prification.
• Ab raised in
  Mouse
• Type
  Monoclonal
• Immunoglobulin
  IgG
• Spicific to
  Vinculin antibody is human, mouse, rat, rabbit and chicken reactive. At least three isoforms of Vinculin are known to exist.
• Antigen
  Vinculin antibody was made against a 23 amino acid peptide near the amino terminus of human Vinculin.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  Vinculin antibody can be used for detection of Vinculin by Western blot at 0.5 - 1 ug/ml.
• Suspention pH azide
  Vinculin Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  Vinculin antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human, Mouse, Rat, Rabbit, Chicken
• Omim nr
  4507877
• Ncbi nr
  NP_003364
• KDa
  Predicted: 117 kDa Observed: 120 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  7414
• GENE symbol
  VCL
• Antigene name
  vinculin
• Source
  homo sapiens
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Vinculin   [7E10]  
• Short name
  anti-Vinculin Antibody [7E10]
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toVinculin (antibody to-) [7E10]
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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