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PS48 for cell activation

PS48 for cell activation is available 0 time from Biovision labs

Description An allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 μM). Binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site. It has recently been found that a combination of PS48, sodium butyrate (Cat. No. 1609-1000), a histone deacetylase inhibitor and the gene Oct-4, could enhance the reprogramming efficiency of keratinocytes isolated from human skin or hair follicles over 25-fold.
Peptide sequence N/A
CAS number 1180676-32-7
Molecular weight 286.75
Category Biochemicals
Other name (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoic acid
Molecular formula C₁₇H₁₅ClO₂
Physical appearance White to off-white solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥95% by HPLC
Reconstitute instructions DMSO (100 mM) or EtOH (50 mM)
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 24 months
Storage instructions Protect from air and light
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetPS48 for activation
Short name PS48 for activation
Technique activation
Alternative name PS48 to measure cellular activation
Tissue cell
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