Apo-SAA Recombinant Protein

• Catalog number
  40-129
• Price
  Please ask
• Size
  0.01 mg, 0.05 mg

• About recombinant protein
  Human apo-SAA is a 104 amino acid polypeptide that circulates primarily in association with high-density lipoproteins (HDL). The level of apo-SAA, normally 1-5 μg/mL in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apo-lipoprotein. The human SAA gene codes for a 122 amino acid polypeptide, which contains an 18 amino acid N-terminal signal sequence. Recombinant Apo-SAA is a consensus SAA molecule corresponding to human apo-SAA1alpha except for the presence of an N-terminal methionine and substitution of asparagine for aspartic acid at position 60 and arginine for histidine at position 71(the later two substituted residues are present in apo-SAA2beta).
• Other name of the recombinant
  SAA, PIG4, SAA2, TP53I4, Serum amyloid A-1 protein, Amyloid fibril protein AA, SAA
• Recombinant in
  E. coli
• SEQUENCE
  MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS NARENIQRFF GRGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY
• Activity
  For most in vitro applications, apo - SAA exerts its biological activity in the concentration range of 10 - 50 μg/mL.
• Keep at
  The lyophilized Apo-SAA recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Apo-SAA is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Apo-SAA recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  40316912
• Accession nr
  NP_000322.2
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  6288
• Gene name
  serum amyloid A1
• Source
  Homo sapiens
• Uniprot
  P0DJI8
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Apo-SAA   Protein  
• Gene symbol
  SAA1
• Short name
  Apo-SAA Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Apo-SAA Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:10513
• Gene
  SAA1
• Long gene name
  serum amyloid A1
• Synonyms gene
  • SAA
• Synonyms
  • PIG4
  • TP53I4
• GenBank acession
  • M10906
• Locus
  11p15.1
• Discovery year
  1988-01-18
• Entrez gene record
  6288
• Pubmed identfication
  • 2595451
  • 9305847
• RefSeq identity
  • NM_199161
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000166147

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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