Macrophage Colony Stimulating Factor Receptor (M-CSFR, CSF-1) (APC)

  • Catalog number
    GEN607241
  • Price
    Please ask
  • Size
    100 Tests
  • Also known as
    Macrophage Colony Stimulating Factor Receptor
  • Other names
    macrophage colony stimulating factor receptor; Macrophage colony-stimulating factor 1 receptor; macrophage colony-stimulating factor 1 receptor; CSF-1-R; CD115 antigen; FMS proto-oncogene; OTTHUMP00000160525; OTTHUMP00000224093; proto-oncogene c-Fms; macrophage colony stimulating factor I receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; colony stimulating factor 1 receptor; Proto-oncogene c-Fms
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    CSF1R; CSF1R; FMS; CSFR; FIM2; C-FMS; CD115; FMS
  • Gene name synonims
    CSF1R; CSF1R; FMS; CSFR; FIM2; C-FMS; CD115; FMS
  • Other gene names
    CSF1R; CSF1R; FMS; CSFR; FIM2; C-FMS; CD115; FMS
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG1
  • Clone
    9L842
  • Host organism
    Mouse (Mus musculus)
  • Source organism
    Human (Homo sapiens)
  • Species reactivity
    Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes human M-CSFR.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    Affinity Purified by Protein G affinity chromatography.
  • Form Appearance
    Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with APC.
  • Concentration
    N/A
  • Storage and shipping
    May be stored at Store the antibody at +4 degrees Celsius. before opening. DO NOT FREEZE! Stable at Store the antibody at +4 degrees Celsius. as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer. Freezing APC conjugates will result in a substantial loss of enzymatic activity. APC conjugates are sensitive to light.
  • Tested applications
    Flow Cytometry (FC/FACS)
  • Description
    Colonies can be formed by stimulating factors or recombinant GM-CSF and CSFs activity expressed in Units compared to a standard. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Gene target
    Macrophage   Colony   Stimulating   Factor   Receptor   M-CSFR   CSF-1   APC  
  • Gene symbol
    CSF1, CPT1B, CSF2, IRAK3, PGAM2, CYP20A1, USP16, CYB5B, APC, H3C14
  • Short name
    Macrophage Colony Stimulating Factor Receptor (M-CSFR, CSF-1) (APC)
  • Label
    APC
  • Alternative name
    Anti-Macrophage Colony Stimulating Factor Receptor (M-CSFR, CSF-1) (APC)
  • Alternative to gene target
    adenomatous polyposis coli, BTPS2 and DP2 and DP2.5 and DP3 and GS and PPP1R46, APC and IDBG-37007 and ENSG00000134982 and 324, microtubule plus-end binding, nuclei, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT.25770 and IDBG-644937 and ENSBTAG00000018852 and 533233
Gene info
Gene info
Gene info
Gene info
  • Identity
    HGNC:17020
  • Gene
    IRAK3
  • Long gene name
    interleukin 1 receptor associated kinase 3
  • Synonyms gene name
    • interleukin-1 receptor-associated kinase 3
  • Synonyms
  • GenBank acession
  • Locus
    12q14.3
  • Discovery year
    2002-07-17
  • Entrez gene record
    11213
  • Pubmed identfication
  • Classification
    • MicroRNA protein coding host genes
  • VEGA ID
    OTTHUMG00000169002
Gene info
  • Identity
    HGNC:8889
  • Gene
    PGAM2
  • Long gene name
    phosphoglycerate mutase 2
  • Synonyms gene name
    • phosphoglycerate mutase 2 (muscle)
  • Synonyms
  • Locus
    7p13
  • Discovery year
    1989-06-30
  • Entrez gene record
    5224
  • Classification
    • Phosphoglycerate mutases
    • Bisphosphoglycerate phosphatases
  • VEGA ID
    OTTHUMG00000155355
Gene info
  • Identity
    HGNC:20576
  • Gene
    CYP20A1
  • Long gene name
    cytochrome P450 family 20 subfamily A member 1
  • Synonyms gene name
    • cytochrome P450, family 20, subfamily A, polypeptide 1
  • Synonyms
  • GenBank acession
  • Locus
    2q33.2
  • Discovery year
    2003-03-20
  • Entrez gene record
    57404
  • RefSeq identity
  • Classification
    • Cytochrome P450 family 20
  • VEGA ID
    OTTHUMG00000132854
Gene info
  • Identity
    HGNC:12614
  • Gene
    USP16
  • Long gene name
    ubiquitin specific peptidase 16
  • Synonyms gene name
    • ubiquitin specific protease 16
  • Synonyms
  • GenBank acession
  • Locus
    21q21
  • Discovery year
    1999-07-09
  • Pubmed identfication
  • Classification
    • Ubiquitin specific peptidases
  • VEGA ID
    OTTHUMG00000078802
Gene info
Gene info
Gene info
MeSH Data
  • Name
    Colony-Forming Units Assay
  • Concept
    Scope note: A cytologic technique for measuring the functional capacity of stem cells by assaying their activity.
  • Tree numbers
    • E01.370.225.500.383
    • E05.200.500.383
    • E05.242.383
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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