Syntrophin-1 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-10221R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  Syntrophin-1 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-Syntrophin-1 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Syntrophin-1
• Specificity
  This is a highly specific antibody against Syntrophin-1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Syntrophin-1
• Gene ID Number
  6640
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013].
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  Syntrophin alpha 1; SNTA1_HUMAN; Alpha-1-syntrophin; 59 kDa dystrophin-associated protein A1 acidic component 1; Pro-TGF-alpha cytoplasmic domain-interacting protein 1; TACIP1; Syntrophin-1.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-Syntrophin-1 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  Syntrophin-1  
• Gene symbol
  SNTG1, SNTB1, SNTA1
• Short name
  Anti-Syntrophin-1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  Syntrophin-1 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13740
• Gene
  SNTG1
• Long gene name
  syntrophin gamma 1
• Synonyms
  • SYN4
  • G1SYN
• Synonyms name
  • Gamma-1-syntrophin
• GenBank acession
  • AJ003030
• Locus
  8q11.21
• Discovery year
  2000-10-20
• Entrez gene record
  54212
• Pubmed identfication
  • 10747910
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000164257

Gene info

• Identity
  HGNC:11168
• Gene
  SNTB1
• Long gene name
  syntrophin beta 1
• Synonyms gene
  • SNT2B1
• Synonyms gene name
  • syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
• Synonyms
  • 59-DAP
  • A1B
  • BSYN2
  • TIP-43
  • SNT2
• Synonyms name
  • tax interaction protein 43
• GenBank acession
  • AF028828
• Locus
  8q24.12
• Discovery year
  1994-12-14
• Entrez gene record
  6641
• Pubmed identfication
  • 8183929
  • 9482110
• RefSeq identity
  • NM_021021
• Classification
  • PDZ domain containing
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000165041

Gene info

• Identity
  HGNC:11167
• Gene
  SNTA1
• Long gene name
  syntrophin alpha 1
• Synonyms gene
  • SNT1
• Synonyms gene name
  • syntrophin, alpha 1 (dystrophin-associated protein A1, 59kD, acidic component)
• Synonyms
  • TACIP1
  • LQT12
• Synonyms name
  • pro-TGF-alpha cytoplasmic domain-interacting protein 1
  • dystrophin-associated protein A1, 59kDa, acidic component
• GenBank acession
  • U40571
• Locus
  20q11.21
• Discovery year
  1994-12-14
• Entrez gene record
  6640
• Pubmed identfication
  • 8576247
  • 8612778
• RefSeq identity
  • NM_003098
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000032259
• Locus Specific Databases
  • SNTA1 database at LOVD-China
  • LRG_332

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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