anti-ETS2 Antibody

  • Catalog number
    31-170
  • Price
    Please ask
  • Size
    50 ug
  • Gene info
    ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).
  • Gene names
    ETS2, ETS2IT1
  • Antibodie s label
    unlabelled serum
  • Purity
    Antibody is purified by peptide affinity chromatography method.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Antigen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ETS2.
  • Immuno application
    ELISA, Western Blot
  • Antibody advice
    ETS2 antibody can be used for detection of ETS2 by ELISA at 1:1562500. ETS2 antibody can be used for detection of ETS2 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
  • Suspention pH azide
    Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
  • Keep at
    For short periods of storage (days) store at 4 grades C. For longer periods of storage, store ETS2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
  • Works with
    Human, Mouse
  • Omim nr
    4885221
  • Ncbi nr
    NP_005230
  • KDa
    53 kDa
  • Vial with antibody
    Lyophilized
  • Quantity per ml
    1 mg/ml
  • NCBI GENE nr
    2114
  • GENE symbol
    ETS2
  • Antigene name
    v-ets avian erythroblastosis virus E26 oncogene homolog 2
  • Source
    Homo sapiens
  • Protein nr
    P15036
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    ETS2  
  • Gene symbol
    ETS2
  • Short name
    anti-ETS2 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toETS2 (antibody to-)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    ETS proto-oncogene 2, transcription factor
  • Synonyms gene name
    • v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
    • v-ets avian erythroblastosis virus E26 oncogene homolog 2
  • Locus
  • Discovery year
    2001-06-22
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • ETS transcription factor family
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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