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c Kit Tyr721 Antibody ALEXA FLUOR

c Kit Tyr721 Antibody ALEXA FLUOR is available 5 times from Bioss primary conjugated antibodies. alexa fluor labs

bs-3242R-A350 | c-Kit(Tyr721) Antibody, ALEXA FLUOR 350 size: 100ul | 408.10 USD


bs-3242R-A488 | c-Kit(Tyr721) Antibody, ALEXA FLUOR 488 size: 100ul | 408.10 USD


bs-3242R-A555 | c-Kit(Tyr721) Antibody, ALEXA FLUOR 555 size: 100ul | 408.10 USD

Catalog number bs-3242R-A555
Price 408.10 USD
Size 100ul
Long name c-Kit(Tyr721) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
Also known as Anti-c-Kit Tyr721 PAb ALEXA FLUOR 555
Conjugated with ALEXA FLUOR® 555
Excitation emission 553nm/568nm
Properties For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation Alexa Fluor,ALEXA FLUOR 555
French translation anticorps
Alternative name c-Kit(Tyr721) Polyclonal Antibody, ALEXA FLUOR 555
Product images
    #.png#bs#.jpgFormalin-fixed and paraffin embedded rat kidney tissue labeled with Anti-Phospho-c-Kit(Tyr721) Polyclonal Antibody, Unconjugated (bs-3242R) followed by conjugation to the secondary antibody and DAB stainingFormalin-fixed and paraffin embedded human lung carcinoma  labeled with Rabbit Anti-c-Kit(Tyr721) Polyclonal Antibody, Unconjugated (bs-3242R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Product files

bs-3242R-A594 | c-Kit(Tyr721) Antibody, ALEXA FLUOR 594 size: 100ul | 408.10 USD


bs-3242R-A647 | c-Kit(Tyr721) Antibody, ALEXA FLUOR 647 size: 100ul | 408.10 USD

Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen c-Kit Tyr721
Specificity This is a highly specific antibody against c-Kit Tyr721.
Modification Phosphorylation
Modification Site Tyr721
Clonality Polyclonal
Clone Polyclonal antibody
Concentration 1ug per 1ul
Immunogen range 700-750/976
Subcellular location Cytoplasm
Source KLH conjugated synthetic phosphopeptide derived from human c-Kit around the phosphorylation site of Tyr721
Gene ID Number 3815
Swiss Prot P10721
Tested applications IF(IHC-P)
Recommended dilutions IF(IHC-P)(1:50-200)
Crossreactivity Human, Mouse, Rat
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor. Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B. Promotes phosphorylation of PIK3R1, CBL, CRK (isoform Crk-II), LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, SRC and SHC1.
Purification Purified by Protein A.
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Synonyms PBT; SCFR; C-Kit; CD117; Mast/stem cell growth factor receptor Kit; Piebald trait protein; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; KIT
Gene targetc-Kit(Tyr721
Short name Anti-c-Kit Tyr721
Technique Antibody
Isotype Immunoglobulin G (IgG)
Alternative technique antibodies
Alternative to gene target v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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Anti-c-Kit Tyr721 | Technique alternative | 01011199281
EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • c-Kit(Tyr721
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