Rabbit anti Retinoic Acid Receptor Beta (RAR Beta/NR1B2) (RARB)
-
Catalog numberX2137P
-
PricePlease ask
-
Size50 μg
-
-
CategoryPrimary Antibodies
-
Long descriptionRetinoic acid receptor beta (RAR beta), a NR1 Thyroid Hormone-Like Receptor, is involved in the regulation of cell growth, differentiation, apoptosis, and carcinogenesis. RAR beta forms heterodimers with the retinoic acid X receptor (RXR) and binds to the direct repeat 1 (DR1) sequence of target DNA. A growing body of evidence supports the hypothesis that RAR beta is a tumor-suppressor gene. Altered expression of RAR beta has been linked to cancers, including those of the head and neck, lung, esophagus, breast, pancreas, and cervix. Three isoforms of RAR beta, beta 1, beta 2, and beta 4, have been documented in humans.
-
Antibody come from3rd cytoplasmic domain of human
-
Other descriptionPhosphate buffered saline containing 0.1% sodium azide. Immunoaffinity Purification
-
ClonePolyclonal
-
Antigen antibody binding interactionRabbit anti Retinoic Acid Receptor Beta (RAR Beta/NR1B2) (RARB) Antibody
-
Antibody is raised inRabbit
-
Antibody s reacts withHuman
-
Antibody s reacts with these speciesThis antibody doesn't cross react with other species
-
Antibody s specificityNo Data Available
-
ApplicationImmunohistochemistry
-
Antibody s suited forOptimal concentration should be evaluated by serial dilutions. ( WrkConcMin: 10 µg/ml)
-
StorageLong term: -70ºC; Short term: +4ºC
-
Relevant referencesno information yet
-
Protein numbersee ncbi
-
WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
AboutRabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin nameOryctolagus cuniculus
-
Gene target
-
Gene symbolRARB, RARB-AS1, RARA, RAB40B, PRAM1, RAB40A
-
Short nameRabbit anti Retinoic Acid Receptor Beta (RAR Beta/NR1B2) (RARB)
-
TechniqueRabbit, anti, antibody to
-
HostRabbit, Rabbits
-
Isotypenot specified
-
Labelunlabeled
-
Alternative nameproduction species: rabbit antibody to Retinoic Acid Receptor b (RAR b/NR1B2) (retinoic acid receptor, b)
-
Alternative techniquerabbit-anti, antibodies
-
Alternative to gene targetretinoic acid receptor, beta, HAP and MCOPS12 and NR1B2 and RRB2, RARB and IDBG-22486 and ENSG00000077092 and 5915, retinoid X receptor binding, nuclei, Rarb and IDBG-133480 and ENSMUSG00000017491 and 218772, RARB and IDBG-630392 and ENSBTAG00000011518 and 100295410
-
Gene info
-
Identity
-
Gene
-
Long gene nameretinoic acid receptor beta
-
Synonyms gene name
- retinoic acid receptor, beta
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1989-05-16
-
Entrez gene record
-
RefSeq identity
-
Classification
- Retinoic acid receptors
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameRARB antisense RNA 1
-
Locus
-
Discovery year2018-09-28
-
Entrez gene record
-
RefSeq identity
-
Classification
- Antisense RNAs
Gene info
-
Identity
-
Gene
-
Long gene nameretinoic acid receptor alpha
-
Synonyms gene name
- retinoic acid receptor, alpha
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1988-06-09
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Retinoic acid receptors
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameRAB40B, member RAS oncogene family
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2002-02-22
-
Entrez gene record
-
Pubmed identfication
-
Classification
- RAB, member RAS oncogene GTPases
- MicroRNA protein coding host genes
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namePML-RARA regulated adaptor molecule 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2005-07-04
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameRAB40A, member RAS oncogene family
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2002-02-22
-
Entrez gene record
-
Pubmed identfication
-
Classification
- RAB, member RAS oncogene GTPases
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
