Recombinant Mouse TFIIH basal transcription factor complex helicase XPD subunit (Ercc2)
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Catalog numberMBS1031801
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PricePlease ask
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Size0.02 mg (E-Coli)
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Products_typeRecombinant Protein
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Products_short_name[TFIIH basal transcription factor complex helicase XPD subunit (Ercc2)]
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Other_names[general transcription and DNA repair factor IIH helicase subunit XPD; General transcription and DNA repair factor IIH helicase subunit XPD; general transcription and DNA repair factor IIH helicase subunit XPD; excision repair cross-complementing rodent repair deficiency, complementation group 2; CXPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; Xeroderma pigmentosum group D-complementing protein]
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Products_gene_name[Ercc2]
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Other_gene_names[Ercc2; Ercc2; XPD; CXPD; Ercc-2; RCO015; AA407812; AU020867; AW240756; Mhdarco15; Xpd; TFIIH subunit XPD]
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Purity>85% (SDS-PAGE)
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FormLyophilized or liquid (Format to be determined during the manufacturing process)
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Storage_stabilityStore at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolGTF2H4, GTF2H1, GTF2H3, ERCC2, GTF2H2, GTF2H5
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Short nameRecombinant Mouse TFIIH basal transcription factor complex helicase XPD subunit (Ercc2)
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TechniqueRecombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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HostE Coli or Yeast or Baculovirus or Mammalian Cell
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SpeciesMouse, Mouses
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Alternative nameRec. Mouse TFIIH basal transcription factor aggregate helicase XPD functionnal sequence (excision repair cross-complementing rodent repair deficiency, complementation family 2)
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Alternative techniquerec, murine
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Alternative to gene targetexcision repair cross-complementing rodent repair deficiency, complementation group 2, COFS2 and EM9 and TFIIH and TTD and XPD, ERCC2 and IDBG-57385 and ENSG00000104884 and 2068, hydrolase activity, nuclei, Ercc2 and IDBG-150400 and ENSMUSG00000030400 and 13871, ERCC2 and IDBG-639452 and ENSBTAG00000002072 and 100125238
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Gene info
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Identity
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Gene
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Long gene namegeneral transcription factor IIH subunit 4
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Synonyms gene name
- general transcription factor IIH, polypeptide 4 (52kD subunit)
- general transcription factor IIH, polypeptide 4, 52kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-08-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nucleotide excision repair
- General transcription factor IIH complex subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namegeneral transcription factor IIH subunit 1
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Synonyms gene name
- general transcription factor IIH, polypeptide 1 (62kD subunit)
- general transcription factor IIH, polypeptide 1, 62kDa
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Synonyms
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Locus
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Discovery year1993-08-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- General transcription factor IIH complex subunits
- Nucleotide excision repair
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namegeneral transcription factor IIH subunit 3
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Synonyms gene name
- general transcription factor IIH, polypeptide 3 (34kD subunit)
- general transcription factor IIH, polypeptide 3, 34kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-11-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- General transcription factor IIH complex subunits
- Nucleotide excision repair
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameERCC excision repair 2, TFIIH core complex helicase subunit
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Synonyms gene
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Synonyms gene name
- xeroderma pigmentosum complementary group D
- excision repair cross-complementing rodent repair deficiency, complementation group 2
- excision repair cross-complementation group 2
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Xeroderma pigmentosum complementation groups
- ERCC excision repair associated
- DNA helicases
- General transcription factor IIH complex subunits
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namegeneral transcription factor IIH subunit 2
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Synonyms gene name
- general transcription factor IIH, polypeptide 2 (44kD subunit)
- general transcription factor IIH, polypeptide 2, 44kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-11-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nucleotide excision repair
- General transcription factor IIH complex subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namegeneral transcription factor IIH subunit 5
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Synonyms gene
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Synonyms gene name
- chromosome 6 open reading frame 175
- trichothiodystrophy
- general transcription factor IIH, polypeptide 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-11-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- General transcription factor IIH complex subunits
- Nucleotide excision repair
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
- E05.599.495
