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Human CellExp Progranulin Recombinant

Human CellExp Progranulin Recombinant is available 24 times from Biovision labs

4737-10 | Human CellExp Progranulin (untagged), Human Recombinant size: 10 μg | 480.17 USD

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4737-50 | Human CellExp Progranulin (untagged), Human Recombinant size: 50 μg | 1,138.18 USD

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4733-50 | Human CellExp Progranulin (untagged), Mouse Recombinant size: 50 μg | 1,138.18 USD

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4733-10 | Human CellExp Progranulin (untagged), Mouse Recombinant size: 10 μg | 462.38 USD

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4736-50 | Human CellExp Progranulin (untagged), Rat Recombinant size: 50 μg | 1,138.18 USD

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4736-10 | Human CellExp Progranulin (untagged), Rat Recombinant size: 10 μg | 480.17 USD

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4738-100 | Human CellExp Progranulin, Human Recombinant size: 100 µg | 2,602.39 USD

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4738-10 | Human CellExp Progranulin, Human Recombinant size: 10 µg | 456.46 USD

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4734-50 | Human CellExp Progranulin, Mouse Recombinant size: 50 μg | 1,084.82 USD

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4734-10 | Human CellExp Progranulin, Mouse Recombinant size: 10 μg | 438.67 USD

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4735-10 | Human CellExp Progranulin, Rat Recombinant size: 10 μg | 438.67 USD

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4735-50 | Human CellExp Progranulin, Rat Recombinant size: 50 μg | 1,084.82 USD

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4737-10 | Human CellExp™ Progranulin (untagged), Human Recombinant size: 10 μg | 387.69 USD

Catalog number 4737-10
Supplier Biovision
Price 387.69 USD
Size 10 μg
Background Progranulin (PGRN), also called proepithelin and PC cell-derived growth factor, is a single precursor protein of granulins which are a family of secreted, glycosylated peptides. It is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of fronto-temporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer‘s Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
Concentration 1 mg/ml
Molecular weight ~65.0 kDa
Synonym Recombinant Human Progranulin (Untagged)
Other name Proepithelin, PEPI, PC Cell-derived Growth Factor.
NCBI gene number 2896
Gene source Human
NCBI number P28799
Purification ≥95%
Tested applications SDS-PAGE, N/A
Biological activity N/A
Physical appearance Liquid
Physical properties 0.2 μm-filtered solution in PBS, pH 7.2.
How to reconstitute N/A
Aa sequence Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional amino acids.
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetCellExp™ Progranulin untagged
Short name CellExp™ Progranulin (untagged) Recombinant
Technique Recombinant
Species Humans
Alternative name H. sapiens CellExp™ Progranulin (untagged), H. sapiens recombinant
Product images
    #Human#.jpg#0#.jpegHuman CellExp™ Progranulin (untagged), Human Recombinant

4737-50 | Human CellExp™ Progranulin (untagged), Human Recombinant size: 50 μg | 1,103.79 USD

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4733-10 | Human CellExp™ Progranulin (untagged), Mouse Recombinant size: 10 μg | 368.72 USD

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4733-50 | Human CellExp™ Progranulin (untagged), Mouse Recombinant size: 50 μg | 1,103.79 USD

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4736-10 | Human CellExp™ Progranulin (untagged), Rat Recombinant size: 10 μg | 387.69 USD

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4736-50 | Human CellExp™ Progranulin (untagged), Rat Recombinant size: 50 μg | 1,103.79 USD

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4738-100 | Human CellExp™ Progranulin, Human Recombinant size: 100 µg | 2,696.05 USD

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4738-10 | Human CellExp™ Progranulin, Human Recombinant size: 10 µg | 362.79 USD

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4734-50 | Human CellExp™ Progranulin, Mouse Recombinant size: 50 μg | 1,045.70 USD

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4734-10 | Human CellExp™ Progranulin, Mouse Recombinant size: 10 μg | 342.64 USD

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4735-50 | Human CellExp™ Progranulin, Rat Recombinant size: 50 μg | 1,045.70 USD

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4735-10 | Human CellExp™ Progranulin, Rat Recombinant size: 10 μg | 342.64 USD

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Taglines Regulator of cell growth, wound healing, and tumorigenesis
Biomolecule/Target NA
NCBI Gene Symbol GRN
Recombinant Yes
Source HEK 293 cells
Activity (Specifications/test method) N/A
Results N/A
Storage Temp. -20°C
Shipping Gel pack
Shelf Life 1 year
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
NCBI gene GRN
Tested activity N/A
Reesults N/A
Binding ability N/A
Unit N/A
Storage condition -20°C
Shipping under Gel pack
Before use Centrifuge the vial prior to opening.
Notes For Research Use Only! Not to be used in humans
Alternative technique rec
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CellExp™ Progranulin (untagged) Recombinant | Technique alte
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