Daxx Antibody

• Catalog number
  3229-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  Daxx
• Target Alternative Name
  Death domain-associated protein 6, ETS1-associated protein 1, Fas death domain-associated protein
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide in the middle of the sequence (BV-M28)
• Accession
  Q9UER7
• Gene Id
  1616
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  30 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
• Purification
  Affinity purified
• Application
  Western blot
• Positive Control
  Western blot: Rat Kidneylysate
• Application And Usages
  Western blot: 1:200
• Description
  Apoptosis can be induced by certain cytokines including TNF and Fas ligand through binding to their respective death domain (DD) containing receptors, TNFR1 and Fas. Cell death signals can then be transduced by DD-containing adapter molecules and members of the caspase family. A novel DD-containing adapter molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx binds to the Fas DD and activates a FADD-independent death pathway that involves the stress activated c-Jun NH2-terminal kinase (JNK). Daxx activates the JNK kinase kinase ASK1 that is also known as MAPKKK5. FADD and Daxx activate two independent pathways downstream of Fas. Daxx mRNA is widely expressed in fetal and adult tissues with the highest amounts being found in the testis.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Daxx  
• Gene symbol
  DAXX
• Short name
  Daxx Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  death-domain associated protein (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  death-domain associated protein, BING2 and DAP6 and EAP1, DAXX and IDBG-82726 and ENSG00000204209 and 102723452,1616, androgen receptor binding, nuclei, Daxx and IDBG-168138 and ENSMUSG00000002307 and 13163, DAXX and IDBG-629026 and ENSBTAG00000016830 and 504336

Gene info

• Identity
  HGNC:2681
• Gene
  DAXX
• Long gene name
  death domain associated protein
• Synonyms gene name
  • death-associated protein 6
• Synonyms
  • DAP6
• GenBank acession
  • AF006041
• Locus
  6p21.32
• Discovery year
  1998-03-25
• Entrez gene record
  1616
• Pubmed identfication
  • 9407001
  • 9215629
• VEGA ID
  OTTHUMG00000031203

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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