anti-ABL2 Antibody [1H1B11]
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Catalog number
32-104
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Price
Please ask
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Size
0.1 mL
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Gene info
ABL2(ARG, Abelson-related gene) is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. c-Abl shows both cytoplasmic and nuclear localization,c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl.
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Gene names
ABLL, ARG, Abelson murine leukemia viral oncogene homolog 2ARG, ABLL
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Antibodie s label
unlabelled serum
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Ab raised in
Mouse
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Type
Monoclonal
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Monoclonal
1H1B11
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Immunoglobulin
IgG1
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Antigen
Ni-NTA purified truncated recombinant ABL2 expressed in E. Coli strain BL21 (DE3).
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Immuno application
ELISA, Western Blot, immuno fluorescence
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Antibody advice
DilutionWestern Blot:1:200 - 1:1,000 IF:1:100 - 1:500ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
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Suspention pH azide
Ascitic fluid containing 0.03% sodium azide.
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Keep at
ABL2 monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Human
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Omim nr
1168268
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Ncbi nr
P42684
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NCBI GENE nr
27
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GENE symbol
ABL2
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Antigene name
c-abl oncogene 2, non-receptor tyrosine kinase
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Source
Homo sapiens
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Protein nr
P42684
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
ABL2
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Short name
anti-ABL2 Antibody [1H1B11]
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toABL2 (antibody to-) [1H1B11]
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Alternative technique
antibodies
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Alternative to gene target
v-abl Abelson murine leukemia viral oncogene homolog 2, ABLL and ARG, ABL2 and IDBG-105099 and ENSG00000143322 and 27, transferase activity, Cytoplasm, Abl2 and IDBG-200390 and ENSMUSG00000026596 and 11352, BT.62162 and IDBG-636736 and ENSBTAG00000015026 and 511845
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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