Smad7 + Smad6 Antibody

• Catalog number
  bs-0566R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Smad7 + Smad6 Primary Polyclonal Antibody
• Also known as
  Smad7 + Smad6 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Smad7 + Smad6
• Specificity
  This is a highly specific antibody against Smad7 + Smad6.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  1-50/426
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Smad7
• Gene ID number
  4092
• Swiss Prot
  O15105
• Tested Applications
  WB, ELISA, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), ELISA(1:500-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator (By similarity).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CRCS3; MADH7; MADH8; Mothers against decapentaplegic homolog 7; MAD homolog 7; Mothers against DPP homolog 7; Mothers against decapentaplegic homolog 8; MAD homolog 8; Mothers against DPP homolog 8; SMAD family member 7; SMAD 7; Smad7; hSMAD7
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Smad7   Smad6  
• Short name
  Anti-Smad7 + Smad6
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Smad7 + Smad6 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  SMAD family member 7, CRCS3 and MADH7 and MADH8, SMAD7 and IDBG-3195 and ENSG00000101665 and 4092, transforming growth factor beta receptor, nuclei, Smad7 and IDBG-158890 and ENSMUSG00000025880 and 17131, SMAD7 and IDBG-644653 and ENSBTAG00000012441 and 535916

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products