Integrin alphaV beta3 (CD51/CD61, RGD-dependent Vitronectin Receptor) (FITC) Antibody
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Catalog numberGEN606138
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PricePlease ask
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Size100ug
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Also known asIntegrin alphaV beta3
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Other namesintegrin beta-3; N/A; integrin beta-3; beta3 integrin; integrin beta 3; glycoprotein GPIIIa; N/A; N/A
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameITGB3; N/A; CD61; N/A
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Gene name synonimsITGB3; N/A; CD61; N/A
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Other gene namesITGB3; N/A; CD61; N/A
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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Clone9G192
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Host organismMouse (Mus musculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes human alpha-V/beta-3 integrin present on human endothelium cells.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodAffinity Purified.
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Form AppearanceSupplied as a liquid in PBS, 1% BSA, 0.02% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
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ConcentrationN/A
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Storage and shippingFor long-term storage and to avoid repeated freezing and thawing, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer. FITC conjugates are sensitive to light.
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Tested applicationsFlow Cytometry (FC/FACS)
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This MBS Monoclonals Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MBS Monoclonals FITC is highly sensitive to pH extremes.
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ConjugationAnti-FITC Antibody
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translationanticorps
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Gene target
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Gene symbolITGB3, ITGAV
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Short nameIntegrin alphaV beta3 (CD51/CD61, RGD-dependent Vitronectin Receptor) (FITC) Antibody
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TechniqueAntibody, FITC, antibodies against human proteins, antibodies for, Fluorescein
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LabelFITC
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Alternative nameAnti-Integrin alphaV beta3 (CD51/CD61, RGD-dependent Vitronectin Receptor) (FITC)
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Alternative techniqueantibodies, fluorescine
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Gene info
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Identity
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Gene
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Long gene nameintegrin subunit beta 3
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Synonyms gene
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Synonyms gene name
- integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
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Synonyms
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Synonyms name
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Locus
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Discovery year1988-06-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Integrin beta subunits
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameintegrin subunit alpha V
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Synonyms gene
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Synonyms gene name
- antigen identified by monoclonal antibody L230
- vitronectin receptor
- integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
- integrin, alpha V
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Synonyms
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Locus
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Discovery year1988-07-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Integrin alpha subunits
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data