Prolactin, human recombinant

• Catalog number
  4687-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  Mammotropin, Luterotropic hormone, Lutetropin, Prlr, PRL, luteotropic hormone, LTH, PRLR, PRL-R, PRL R
• Alternative_names
  Mammotropin, Luterotropic hormone, Lutetropin, Prlr, PRL, luteotropic hormone, LTH, PRLR, PRL-R, PRL R
• Description
  An important regulator of immune system with cell cycle related functions
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Purity
  ≥95%
• Biological activity
  The ED₅₀ determined by the dose-dependent stimulation of the proliferation of rat lymphoma, Nb2-11 cells was found to be
• Molecular Weight
  23.3 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Sterile filtered and lyophilized from 10 mM Sodium Phosphate, pH 8.0 + 50 mM NaCl.
• Reconstitution Instructions
  Reconstitute in H₂O to a concentration of 1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
• Background Information
  Prolactin (also known as mammotrophin, luterotropic hormone, and lutetropin) is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, Prolactin plays an immune-regulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Recombinant human Prolactin is a 23 kDa globular protein containing 200 amino acid residues.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Prolactin  
• Gene symbol
  PRL, PIP, PRLR
• Short name
  Prolactin, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Prolactin, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:9445
• Gene
  PRL
• Long gene name
  prolactin
• GenBank acession
  • D00411
• Locus
  6p22.3
• Discovery year
  1986-01-01
• Entrez gene record
  5617
• RefSeq identity
  • NM_000948
• Classification
  • Growth hormone family
  • Neuropeptides
• VEGA ID
  OTTHUMG00000016111

Gene info

• Identity
  HGNC:8993
• Gene
  PIP
• Long gene name
  prolactin induced protein
• Synonyms gene name
  • prolactin-induced protein
• Synonyms
  • GCDFP-15
  • GCDFP15
  • GPIP4
• Synonyms name
  • prolactin-inducible protein
• Locus
  7q34
• Discovery year
  1988-08-19
• Entrez gene record
  5304
• Pubmed identfication
  • 2727805
  • 1955075
• RefSeq identity
  • NM_002652
• VEGA ID
  OTTHUMG00000152635

Gene info

• Identity
  HGNC:9446
• Gene
  PRLR
• Long gene name
  prolactin receptor
• Locus
  5p13.2
• Discovery year
  1989-12-01
• Entrez gene record
  5618
• VEGA ID
  OTTHUMG00000090789

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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