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Apigenin for cell activation

Apigenin for cell activation is available 2 times from Biovision labs

2508-25 | Apigenin for cell activation size: 25 mg | 163.37 USD

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2508-100 | Apigenin for cell activation size: 100 mg | 401.52 USD

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Other name 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Chamomile; Flavone; NSC 83244; Versulin
Supplied with N/A
Description A naturally occurring plant flavone that displays remarkable anti-inflammatory, antioxidant and anti-carcinogenic properties. It selectively inhibits casein kinase II (CK2). Apigenin inhibits CK2 activity in the renal cortex with an IC₅₀ value of 30 µM to improve renal function in a rat model of glomerulonephritis. CK2 inhibition by 20 µM apigenin decreases the degradation of IκBα and down-regulates NF-κB levels in WEHI 231 cells. At 5 µM, it is a potent inhibitor of the synthesis of the inflammatory mediators nitric oxide and prostaglandin E2, reducing inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression by 56% and 64%, respectively, in the macrophage cell line J774A.1.
Category Biochemicals
Molecular formula C₁₅H₁₀O₅
Is it cell-permeable? Yes
Molecular weight 270.2
Storage condition -20°C
Shipping condition Gel pack
Purification ≥98% by HPLC
Peptide sequence No
Is this a salt? No
CAS number 520-36-5
Storage instructions Protect from air and light
Maximum time for storage 24 months
Physical appearance White solid
Reconstitute instructions DMSO (~25 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetApigenin for activation
Short name Apigenin for activation
Technique activation
Alternative name Apigenin to measure cellular activation
Alternative technique immunoglobulin-e
Tissue cell
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