CCR2 Antibody
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Catalog number3415R-100
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PricePlease ask
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Size100 µg
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Antibody TargetCCR2
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Target Alternative NameCCR2A, CCR2B, Chemokine CC Motif Receptor 2, CKR2, Monocyte Chemotactic Protein 1 Receptor,
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat
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Immunogen SequenceSynthetic peptide surrounding to amino acid 353 of rat CCR2
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AccessionNP_068638.1
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Gene Id60463
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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Formulationin phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.
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PurificationAffinity purified
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ApplicationWestern blot
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Application And UsagesWestern blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects ~42 kDa of CCR2 in samples from human, mouse and rat origins. Reactivity to other species has not been determined.
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DescriptionChemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCCR2
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Short nameCCR2 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative namechemokine (C-C motif) receptor 2 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetchemokine (C-C motif) receptor 2, CCR2 and IDBG-30182 and ENSG00000121807 and 729230, protein homodimerization activity, Plasma membranes, BT.63814 and IDBG-647810 and ENSBTAG00000013586 and 539002
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Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine receptor 2
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Synonyms gene
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Synonyms gene name
- chemokine (C-C motif) receptor 2
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Synonyms
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Locus
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Discovery year1995-05-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C-C motif chemokine receptors
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data