This antibody has been succesfully tested for use in following methods:
Target of this antibody:
Formulation of this antibody:
100 µg (0.5 mg/ml) affinity purified rabbit anti-CCR2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% Thimerosal.
Alternative names of antibody target:
CCR2A, CCR2B, Chemokine CC Motif Receptor 2, CKR2, Monocyte Chemotactic Protein 1 Receptor,
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects ~42 kDa of CCR2 in samples from human, mouse and rat origins. Reactivity to other species has not been determined.
Shelf time: 12 months in temp.: -20 deg.C
This antibody reacts with:
Human, mouse, rat
Clonality of antibody:
Synthetic peptide surrounding to amino acid 353 of rat CCR2
How to handle this antibody:
The antibody solution should be gently mixed before use.
Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.
Form of antibody:
Concentration of antibody:
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
antibody to-chemokine (C-C motif) receptor 2 (Antibody to)
Alternative to gene target
chemokine (C-C motif) receptor 2, CCR2 and IDBG-30182 and ENSG00000121807 and 729230, protein homodimerization activity, Plasma membranes, BT.63814 and IDBG-647810 and ENSBTAG00000013586 and 539002