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CTLA4 Lentiviral Vector Human pLenti GIII

CTLA4 Lentiviral Vector Human pLenti GIII is available 6 times from Abm lentivectors labs

LV796635 | CTLA4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) size: 1.0 µg DNA | 364.30 USD

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LV796636 | CTLA4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA) size: 1.0 µg DNA | 364.30 USD

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LV796637 | CTLA4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro) size: 1.0 µg DNA | 364.30 USD

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LV796638 | CTLA4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro) size: 1.0 µg DNA | 364.30 USD

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LV796640 | CTLA4 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a) size: 1.0 µg DNA | 364.30 USD

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LV796639 | CTLA4 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC) size: 1.0 µg DNA | 364.30 USD

Short name CTLA4 Lentiviral Vector ( ) (UbC) (pLenti-GIII-UbC)
Alternative name cytotoxic T-lymphocyte-associated protein 4 Lentiviral integrating Desoxyribonucleic acid sequence (H. sapiens) (UbC) (pLenti-GIII-UbC)
1. Gene info
Identity17934
GenePLA2G3
Long gene name phospholipase A2 group III
Synonyms gene name
  • phospholipase A2, group III
Synonyms
GenBank acession
Locus22q12.2
Discovery year 2002-04-29
Entrez gene record50487
Pubmed identfication
RefSeq identity
Classification
  • Phospholipases
Havana BLAST/BLATOTTHUMG00000151255
2. Gene info
Identity2505
GeneCTLA4
Long gene name cytotoxic T-lymphocyte associated protein 4
Synonyms gene
Synonyms gene name
  • celiac disease 3
  • insulin-dependent diabetes mellitus 12
Synonyms
Locus2q33.2
Discovery year 1989-05-25
Entrez gene record1493
Pubmed identfication
RefSeq identity
Classification
  • CD molecules
  • V-set domain containing
Havana BLAST/BLATOTTHUMG00000132877
MeSH Data
Concept
Scope note:The transfer of bacterial DNA by phages from an infected bacterium to another bacterium. This also refers to the transfer of genes into eukaryotic cells by viruses. This naturally occurring process is routinely employed as a GENE TRANSFER TECHNIQUE.
Tree numbers
  • E05.393.350.800
Additional information
PubMedStudies indicate that Mdm2 has the ability to catalyze both mono- and poly-ubiquitination of p53.
Studies indicate that monoubiquitylation of PCNA allows mutagenic translesion synthesis by damage-tolerant DNA polymerases, polyubiquitylation is required mainly for an error-free pathway that likely involves template switching.
Data indicate that heat shock protein 90kDa (Hsp90) inhibition suppresses 26S proteasome remodeling, unanchored ubiquitin chain production, and aggresome clearance.
Data suggest that ubiquitin (Ub) binding provides a negative feedback loop upon NOD1 and NOD2 (nucleotide-binding oligomerization domain-containing proteins)-dependent activation of receptor-interacting protein kinase 2 (RIP2).
CHBP is an inhibitor of the ubiquitination pathway; it deamidated Gln40 in ubiquitin and ubiquitin-like protein NEDD8 in vitro and during Burkholderia infection; Cif deamidated NEDD8, abolishing activity of neddylated Cullin-RING ubiquitin ligases
The structure of UbcH8 does not undergo a significant conformational change upon forming a complex with ubiquitin.
Studies indicate that the involvement of the degradation-linked K48-ubiquitin signal and the proteasome at the sites of DSBs.
Studies indicate that Non-proteolytic ubiquitylation of chromatin surrounding DSBs, mediated by the RNF8/RNF168 ubiquitin ligase cascade, has emerged as a key mechanism for restoration of genome integrity.
Data show that discoidin domain receptor 2 (DDR2) is linked to a polyubiquitin (Ub) chain predominantly through lysine K27 conjugation and slightly through K33.
Data show that at least three heat shock elements with different configurations, exist in the UBC promoter. All of them are bound by transcription factors belonging to the heat shock factor family clarifying the mechanisms regulating UBC expression.
Gene ontology - Molecular functionprotein binding
RNA binding
protease binding
Entrez Geneubiquitin C  (UBC)
Product images
    #LV#.jpg#Human#.jpg
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Technique Vectors
Species Human
Alternative to gene target cytotoxic T-lymphocyte-associated protein 4, CD and CD152 and CELIAC3 and CTLA-4 and GRD4 and GSE and IDDM12, CTLA4 and IDBG-79215 and ENSG00000163599 and 1493, protein binding, Cell surfaces, Ctla4 and IDBG-159662 and ENSMUSG00000026011 and 12477, CTLA-4 and IDBG-643375 and ENSBTAG00000013170 and 281732
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