Recombinant Human β-Arrestin 1/ARRB1 Protein(C-6His) 50µg

• Catalog number
  PKSH033262-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  Beta-Arrestin-1; Arrestin Beta-1; ARRB1; ARR1
• Activity
  NA
• Sequence
  Met1-Arg418
• Fusion tag
  C-6His
• Accession
  P49407
• Expressed Host
  E.coli
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
• Mol Mass
  48.1 kDa
• AP Mol Mass
  50 kDa
• Formulation
  Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
• Reconstitution
  Please refer to it for detailed information.
• Background
  β-Arrestin-1 (ARRB1) is a cytoplasmic protein that belongs to the arrestin family. ARRB1 is expressed at high levels in peripheral blood leukocytes and the central nervous system. ARRB1 regulates agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. ARRB1 acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. ARRB1 is believed to play a major role in regulating receptor-mediated immune functions. ARRB1 is involved in Toll-like receptor and IL-1 receptor signaling through the interaction with TRAF6.
• Product URL
• PDF URL
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  β-Arrestin   1/ARRB1   Protein   C-6His   50µg  
• Gene symbol
  ARRB1
• Short name
  Recombinant β-Arrestin 1/ARRB1 Protein(C-6His) 50µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens β-Arrestin 1/arrestin, b 1 Protein(C-6His) 50µg
• Alternative technique
  rec
• Alternative to gene target
  arrestin, beta 1, ARB1 and ARR1, ARRB1 and IDBG-64687 and ENSG00000137486 and 102724825,102724972,408, transcription regulatory region DNA binding, nuclei, Arrb1 and IDBG-200741 and ENSMUSG00000018909 and 109689, ARRB1 and IDBG-635576 and ENSBTAG00000020485 and 281637

Gene info

• Identity
  HGNC:711
• Gene
  ARRB1
• Long gene name
  arrestin beta 1
• Synonyms gene
  • ARR1
• Synonyms gene name
  • arrestin, beta 1
• Synonyms name
  • arrestin 2
• GenBank acession
  • BC003636
• Locus
  11q13.4
• Discovery year
  1994-01-10
• Entrez gene record
  408
• Pubmed identfication
  • 8486659
• RefSeq identity
  • NM_004041
• Classification
  • Classical arrestins
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000165444

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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