Caspase 9, Recombinant, Human (ICE-LAP6, Mch6, Apaf 3)

Products_type

Recombinant Protein
Products_short_name

[Caspase 9]
Other_names

[caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine peptidase; caspase-9; caspase 9, apoptosis-related cysteine peptidase
Other_gene_names

[casp9; casp9-A; caspase9; xCaspase-9]
Purity

Highly Purified
Storage_stability

-70 degree C
Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Gene

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Caspase ICE-LAP6 Mch6 Apaf
Gene symbol

CASP9, CASP1, CASP5, CES2, CARD18, CARD16, CASP4, CASP7
Short name

Caspase 9, Recombinant, (ICE-LAP6, Mch6, Apaf 3)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

caspase 9, Rec., H. sapiens (ICE-LAP6, Mch6, Apoptotic protease activating factor 3)
Alternative technique

rec

Identity

HGNC:1511
Gene

CASP9
Long gene name

caspase 9
Synonyms gene name
- caspase 9, apoptosis-related cysteine protease
- caspase 9, apoptosis-related cysteine peptidase
Synonyms
- MCH6
- ICE-LAP6
- APAF-3
- PPP1R56
Synonyms name
- protein phosphatase 1, regulatory subunit 56
GenBank acession
- U60521
Locus

1p36.21
Discovery year

1996-11-11
Entrez gene record

842
Pubmed identfication
- 8663294
- 9390557
RefSeq identity
- NM_032996
Classification
- Caspases
- Apoptosome
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
VEGA ID

OTTHUMG00000002256

Identity

HGNC:1499
Gene

CASP1
Long gene name

caspase 1
Synonyms gene
- IL1BC
Synonyms gene name
- caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase
Synonyms
- ICE
Synonyms name
- caspase-1
- interleukin 1, beta, convertase
GenBank acession
- U13697
Locus

11q22.3
Discovery year

1992-05-07
Entrez gene record

834
Pubmed identfication
- 1373520
- 9250871
RefSeq identity
- NM_033292
Classification
- Caspases
- Caspase recruitment domain containing
VEGA ID

OTTHUMG00000048072

Identity

HGNC:1506
Gene

CASP5
Long gene name

caspase 5
Synonyms gene name
- caspase 5, apoptosis-related cysteine protease
- caspase 5, apoptosis-related cysteine peptidase
Synonyms
- ICE(rel)III
Locus

11q22.3
Discovery year

1996-09-13
Entrez gene record

838
Pubmed identfication
- 7797592
- 9250871
RefSeq identity
- NM_004347
Classification
- Caspases
- Caspase recruitment domain containing
VEGA ID

OTTHUMG00000048073

Identity

HGNC:1505
Gene

CASP4
Long gene name

caspase 4
Synonyms gene name
- caspase 4, apoptosis-related cysteine protease
- caspase 4, apoptosis-related cysteine peptidase
Synonyms
- ICE(rel)II
- ICH-2
- TX
GenBank acession
- U25804
Locus

11q22.3
Discovery year

1996-07-22
Entrez gene record

837
Pubmed identfication
- 7797510
- 9250871
RefSeq identity
- NM_001225
Classification
- Caspases
- Caspase recruitment domain containing
VEGA ID

OTTHUMG00000166078

Identity

HGNC:1508
Gene

CASP7
Long gene name

caspase 7
Synonyms gene name
- caspase 7, apoptosis-related cysteine protease
- caspase 7, apoptosis-related cysteine peptidase
Synonyms
- MCH3
- CMH-1
- ICE-LAP3
GenBank acession
- U37448
Locus

10q25.3
Discovery year

1996-07-22
Entrez gene record

840
Pubmed identfication
- 8521391
- 8576161
RefSeq identity
- NM_033338
Classification
- Caspases
VEGA ID

OTTHUMG00000019076

Name

Models, Chemical
Concept

Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Tree numbers
- E05.599.495