MSH gamma Antibody

• Catalog number
  bs-3918R
• Price
  Please ask
• Size
  0.1ml

• Long name
  MSH gamma Primary Polyclonal Antibody
• Also known as
  MSH gamma PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  MSH gamma
• Specificity
  This is a highly specific antibody against MSH gamma. This antibody will detect Pro-opiomelanocortin, as well as MSH gamma, due to the fact that this protein is contained within this chain, and is then cleaved to produce MSH gamma. MSH gamma itself is too small to be detected by WB.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  77-87/267
• Subcellular location
  Secreted
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MSH gamma
• Gene ID number
  5443
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Gamma MSH; Melanocyte Stimulating Hormone; Melanotropin gamma; POMC; Proopiomelanocortin; COLI_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MSH   gamma  
• Gene symbol
  MC1R, MSX2, POMC
• Short name
  Anti-MSH gamma
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  MSH gamma Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6929
• Gene
  MC1R
• Long gene name
  melanocortin 1 receptor
• Synonyms gene name
  • melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
• Synonyms
  • MSH-R
• Synonyms name
  • alpha melanocyte stimulating hormone receptor
• Locus
  16q24.3
• Discovery year
  1993-07-27
• Entrez gene record
  4157
• Pubmed identfication
  • 8458079
• RefSeq identity
  • NM_002386
• Classification
  • Melanocortin receptors
• VEGA ID
  OTTHUMG00000171163

Gene info

• Identity
  HGNC:7392
• Gene
  MSX2
• Long gene name
  msh homeobox 2
• Synonyms gene
  • PFM1
• Synonyms gene name
  • msh (Drosophila) homeo box homolog 2
  • parietal foramina 1
  • msh homeobox homolog 2 (Drosophila)
• Synonyms
  • CRS2
  • FPP
  • HOX8
  • MSH
  • PFM
• Synonyms name
  • craniosynostosis, type 2
• GenBank acession
  • D26145
• Locus
  5q35.2
• Discovery year
  1993-05-26
• Entrez gene record
  4488
• Pubmed identfication
  • 8668339
  • 8786091
• Classification
  • NKL subclass homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000130556

Gene info

• Identity
  HGNC:9201
• Gene
  POMC
• Long gene name
  proopiomelanocortin
• Synonyms
  • MSH
  • POC
  • CLIP
  • ACTH
  • NPP
  • LPH
• Synonyms name
  • adrenocorticotropin
  • beta-lipotropin
  • alpha-melanocyte stimulating hormone
  • beta-melanocyte stimulating hormone
  • beta-endorphin
  • adrenocorticotropic hormone
  • opiomelanocortin prepropeptide
• Locus
  2p23.3
• Discovery year
  1986-01-01
• Entrez gene record
  5443
• Pubmed identfication
  • 6254047
  • 9620771
• RefSeq identity
  • NM_001035256
• Classification
  • Neuropeptides
• VEGA ID
  OTTHUMG00000094764

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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