DOK1 (Tyr398) Antibody, ALEXA FLUOR 488

• Catalog number
  bs-5290R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  DOK1 (Tyr398) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-DOK1 Tyr398 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  DOK1 Tyr398
• Specificity
  This is a highly specific antibody against DOK1 Tyr398.
• Modification
  Phosphorylation
• Modification Site
  Tyr398
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human DOK1 around the phosphorylation site of Tyr398
• Gene ID Number
  1796
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  DOK1 phospho Y398; DOK1 phospho Tyr398; p-DOK1 phospho Y398; docking protein 1 downstream of tyrosine kinase 1; Docking protein 1 p62dok Downstream of tyrosine kinase 1 pp62.; docking protein 1 62kD downstream of tyrosine kinase 1; Docking protein 1 62kD; Docking protein 1 62kD; Docking protein 1; DOK 1; DOK1; DOK-1; DOK1_HUMAN; Downstream of tyrosine kinase 1; p62dok; P62DOK; pp62; pp62.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-DOK1 Tyr398 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  DOK1   Tyr398  
• Gene symbol
  DOK1, ART4
• Short name
  Anti-DOK1 Tyr398
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  DOK1 (Tyr398) Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  docking protein 1, 62kDa (downstream of tyrosine kinase 1), P62DOK, DOK1 and IDBG-57879 and ENSG00000115325 and 1796, protein binding, nuclei, Dok1 and IDBG-159342 and ENSMUSG00000068335 and 13448, DOK1 and IDBG-631228 and ENSBTAG00000018579 and 514962

Gene info

• Identity
  HGNC:2990
• Gene
  DOK1
• Long gene name
  docking protein 1
• Synonyms gene name
  • docking protein 1, 62kD (downstream of tyrosine kinase 1)
  • docking protein 1, 62kDa (downstream of tyrosine kinase 1)
• Synonyms
  • p62dok
• Synonyms name
  • downstream of tyrosine kinase 1
• GenBank acession
  • U70987
• Locus
  2p13.1
• Discovery year
  1997-07-25
• Entrez gene record
  1796
• Pubmed identfication
  • 9008160
  • 9790776
  • 15546884
• RefSeq identity
  • NM_001381
• VEGA ID
  OTTHUMG00000129956

Gene info

• Identity
  HGNC:726
• Gene
  ART4
• Long gene name
  ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)
• Synonyms gene
  • DO
• Synonyms gene name
  • Dombrock blood group
  • ADP-ribosyltransferase 4 (DO blood group)
  • ADP-ribosyltransferase 4
  • ADP-ribosyltransferase 4 (Dombrock blood group)
• Synonyms
  • DOK1
  • CD297
  • ARTC4
• Synonyms name
  • NAD(+)--protein-arginine ADP-ribosyltransferase 4
• GenBank acession
  • X95826
• Locus
  12p12.3
• Discovery year
  1998-05-11
• Entrez gene record
  420
• Pubmed identfication
  • 9119374
• RefSeq identity
  • NM_021071
• Classification
  • Blood group antigens
  • ADP-ribosyltransferase family
  • CD molecules
• VEGA ID
  OTTHUMG00000168738
• Locus Specific Databases
  • LRG_807

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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