Conjugated Primary Antibodies
Rabbit (Oryctolagus cuniculus)
This is a highly specific antibody against DOK1 Tyr398.
1ug per 1ul
KLH conjugated synthetic phosphopeptide derived from human DOK1 around the phosphorylation site of Tyr398
Gene ID Number
Human, Mouse, Rat
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
Purified by Protein A.
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
DOK1 phospho Y398; DOK1 phospho Tyr398; p-DOK1 phospho Y398; docking protein 1 downstream of tyrosine kinase 1; Docking protein 1 p62dok Downstream of tyrosine kinase 1 pp62.; docking protein 1 62kD downstream of tyrosine kinase 1; Docking protein 1 62kD; Docking protein 1 62kD; Docking protein 1; DOK 1; DOK1; DOK-1; DOK1_HUMAN; Downstream of tyrosine kinase 1; p62dok; P62DOK; pp62; pp62.
Immunoglobulin G (IgG)
Alternative to gene target
docking protein 1, 62kDa (downstream of tyrosine kinase 1), P62DOK, DOK1 and IDBG-57879 and ENSG00000115325 and 1796, protein binding, nuclei, Dok1 and IDBG-159342 and ENSMUSG00000068335 and 13448, DOK1 and IDBG-631228 and ENSBTAG00000018579 and 514962