BAY 11-7082NF-κB Inhibitor

Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Gene target

BAY 11-7082NF-κB Inhibitor
Gene symbol

PIRC52, PIRC51, IGKV1OR2-11, PIRC50, SNORD115-11, SNORD114-11, SNORD116-11, IGHV3OR16-11
Short name

BAY 11-7082NF-κB Inhibitor
Alternative name

BAY 11-7082NF-κB suppressor

Identity

HGNC:5768
Gene

IGKV1OR2-11
Long gene name

immunoglobulin kappa variable 1/OR2-11 (pseudogene)
Synonyms gene name
- immunoglobulin kappa variable 1/OR2-11
- immunoglobulin kappa variable 1/OR2-11 pseudogene
Synonyms
- IGKV1/OR2-11
GenBank acession
- X51885
Locus

2q11.2
Discovery year

2000-04-18
Entrez gene record

28863
Pubmed identfication
- 2111145
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000184518

Identity

HGNC:5635
Gene

IGHV3OR16-11
Long gene name

immunoglobulin heavy variable 3/OR16-11 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable 3/OR16-11
- immunoglobulin heavy variable 3/OR16-11 pseudogene
Synonyms
- IGHV3/OR16-11
GenBank acession
- Z29608
Locus

16p11.2
Discovery year

2000-04-17
Entrez gene record

28305
Classification
- Immunoglobulin heavy (IGH) orphons
VEGA ID

OTTHUMG00000184731