PLC gamma 2 Antibody
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Catalog number3587-100
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PricePlease ask
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Size100 µg
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Antibody TargetPLCg2
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Target Alternative NamePLC, EC 3.1.4.11 , Phosphoinositide phospholipase C , PLC-gamma-2 , Phospholipase C-gamma-2 , PLC-IV , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat
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Immunogen SequenceSynthetic peptide near the C-terminus of human PLCg2
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AccessionAAH18646
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Gene Id5336
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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Formulation100 µg (0.5 mg/ml) peptide affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
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PurificationAffinity purified
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ApplicationWestern blot, Immunoprecipitation, Immunohistochemistry
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Application And UsagesWestern blotting (1-4 µg/ml), immunoprecipitation (20 µg/ml), and Immunohistochemistry (20 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 150 kDa PLCg2 in samples from human, mouse, and rat origins. The antibody does not cross-react with PLCg1.
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DescriptionPLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCg, PLCd, and PLCe. In response to extracellular stimuli (e.g., hormone, growth factors, neurotransmitters), PLC hydrolizes phosphatidylinositol 4,5-biphosphate (PIP2) into two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PLCg2 is engaged in antigen-dependent signaling in B-cells and collagen-dependent signaling in platelets.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPLCB1, PLCL1, PLCG1, PLCH2, PDIA3
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Short namePLC gamma 2 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative namePLC g 2 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namephospholipase C beta 1
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Synonyms gene name
- phospholipase C, beta 1 (phosphoinositide-specific)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-21
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Entrez gene record
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Pubmed identfication
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Classification
- Phospholipases
- C2 domain containing phospholipases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephospholipase C like 1 (inactive)
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Synonyms gene
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Synonyms gene name
- phospholipase C, epsilon
- phospholipase C-like 1
- phospholipase C like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-12-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein phosphatase 1 regulatory subunits
- C2 domain containing phospholipases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephospholipase C gamma 1
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Synonyms gene
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Synonyms gene name
- phospholipase C, gamma 1 (formerly subtype 148)
- phospholipase C, gamma 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-05-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
- MicroRNA protein coding host genes
- Phospholipases
- SH2 domain containing
- C2 domain containing phospholipases
- EF-hand domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephospholipase C eta 2
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Synonyms gene
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Synonyms gene name
- phospholipase C-like 4
- phospholipase C, eta 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-07-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EF-hand domain containing
- Phospholipases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein disulfide isomerase family A member 3
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Synonyms gene
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Synonyms gene name
- glucose regulated protein, 58kDa
- protein disulfide isomerase-associated 3
- protein disulfide isomerase family A, member 3
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Synonyms
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Locus
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Discovery year1997-06-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein disulfide isomerases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data