PLC gamma 2 Antibody

  • Catalog number
    3587-100
  • Price
    Please ask
  • Size
    100 µg
  • Antibody Target
    PLCg2
  • Target Alternative Name
    PLC, EC 3.1.4.11 , Phosphoinositide phospholipase C , PLC-gamma-2 , Phospholipase C-gamma-2 , PLC-IV , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human, mouse, rat
  • Immunogen Sequence
    Synthetic peptide near the C-terminus of human PLCg2
  • Accession
    AAH18646
  • Gene Id
    5336
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.5 mg/ml
  • Formulation
    100 µg (0.5 mg/ml) peptide affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
  • Purification
    Affinity purified
  • Application
    Western blot, Immunoprecipitation, Immunohistochemistry
  • Application And Usages
    Western blotting (1-4 µg/ml), immunoprecipitation (20 µg/ml), and Immunohistochemistry (20 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 150 kDa PLCg2 in samples from human, mouse, and rat origins. The antibody does not cross-react with PLCg1.
  • Description
    PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCg, PLCd, and PLCe. In response to extracellular stimuli (e.g., hormone, growth factors, neurotransmitters), PLC hydrolizes phosphatidylinositol 4,5-biphosphate (PIP2) into two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PLCg2 is engaged in antigen-dependent signaling in B-cells and collagen-dependent signaling in platelets.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    PLC   gamma  
  • Gene symbol
    PLCB1, PLCL1, PLCG1, PLCH2, PDIA3
  • Short name
    PLC gamma 2 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    PLC g 2 (antibody to-)
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    phospholipase C gamma 1
  • Synonyms gene
  • Synonyms gene name
    • phospholipase C, gamma 1 (formerly subtype 148)
    • phospholipase C, gamma 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1989-05-31
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Pleckstrin homology domain containing
    • MicroRNA protein coding host genes
    • Phospholipases
    • SH2 domain containing
    • C2 domain containing phospholipases
    • EF-hand domain containing
  • VEGA ID
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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