Bax Antibody
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Catalog numberR30182
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenBax
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB
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Recommended dilutionsWestern blot: 0.5-1ug/ml
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NotesThe stated application concentrations are suggested starting points. Titration of the Bax antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis Bax antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ07812
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PurityAntigen affinity
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DescriptionBcl-2 Associated X Protein is a member of the Bcl-2 gene family. The gene encodes a 21-kDa protein whose association with Bcl-2 is believed to play a critical role in regulating apoptosis. Human BAX gene is located in the q13.3-q13.4 region of human chromosome 19. Bax is an apoptosis-inducing protein that participates in cell death during normal development and in various diseases. It resides in an inactive state in the cytosol of many cells. Bax consists of 9 alpha helices and has extensive amino acid homology with Bcl-2, focused within highly conserved domains I and II. Bax is encoded by six exons and demonstrates a complex pattern of alternative RNA splicing that predicts a 21 kd membrane(alpha) and two forms of cytosolic protein(beta and gamma). BAX and BAK are essential for regulating the number of B cells at both immature and mature developmental stages. They are critical mediators of B cell death induced by multiple stimuli.
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ImmunogenAn amino acid sequence from the N-terminus of human Bax (DELDSNMELQRMIA) was used as the immunogen for this Bax antibody.
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StorageAfter reconstitution, the Bax antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTMBIM7P, TMBIM6, TMBIM1
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Short nameAnti-Bax
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to Bax
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Alternative techniqueantibodies
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Alternative to gene targetBCL2-associated X protein, BCL2L4, BAX and IDBG-61459 and ENSG00000087088 and 581, BH3 domain binding, nuclei, Bax and IDBG-183241 and ENSMUSG00000003873 and 12028, BAX and IDBG-640344 and ENSBTAG00000013340 and 100850136,280730
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Gene info
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Identity
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Gene
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Long gene nametransmembrane BAX inhibitor motif containing 7, pseudogene
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Locus
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Discovery year2013-10-09
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Entrez gene record
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Classification
- Transmembrane BAX inhibitor motif containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametransmembrane BAX inhibitor motif containing 6
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Synonyms gene
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Synonyms gene name
- testis enhanced gene transcript
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1994-08-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Transmembrane BAX inhibitor motif containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametransmembrane BAX inhibitor motif containing 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-08-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Transmembrane BAX inhibitor motif containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data