Fasudil, Monohydrochloride

• Catalog number
  1787-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  1-(5-Isoquinolinesulfonyl)homopiperazine, Monohydrochloride Salt; HA-1077, Monohydrochloride; AT-877
• Description
  A cell-permeable Ca²⁺ antagonist and vasodilator. Inhibits protein kinase A (Ki = 1.6 µM), protein kinase G (Ki = 1.6 µM), myosin light chain kinase (Ki = 36 µM) and Rho kinase (ROCK; IC₅₀ = 10.7 µM. Fasudil also mobilizes adult neural stem cells in vivo.
• CAS Number
  105628-07-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₄H₁₇N₃O₂S•HCl
• Molecular Weight
  327.83
• Cell Permeable
  Yes
• Purity
  ≥99% by HPLC
• Solubilities
  Water (175 mg/ml) or DMSO (10 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  A Rho kinase (ROCK) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  48 months
• MDL Number
  MFCD00943198
• PubChem CID
  163751
• PubChem CID Link
• SMILES
  C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl
• InChi
  InChI=1S/C14H17N3O2S.ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;/h1,3-5,7,11,15H,2,6,8-10H2;1H
• InChi Key
  LFVPBERIVUNMGV-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Fasudil   Monohydrochloride  
• Short name
  Fasudil, Monohydrochloride
• Alternative name
  Fasudil, Monohydrochloride

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