Curcumin, Curcuma longa (High Purity)

  • Catalog number
    1850-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane
  • Description
    Cell-permeable. An antioxidant and dual inhibitor of 5-lipoxygenase (IC₅₀ = 8 µM) and cyclooxygenase (COX) (IC₅₀ = 52 µM). Also inhibits glutathione S-transferase, induction of nitric oxide (NO) in activated macrophages and inhibits EGF-induced tyrosine phosphorylation of EGF receptors. Also shown to be a p300/CREB-binding protein-specific inhibitor of histone acetyltransferase, inhibiting the acetylation of histones H3 and H4 with an IC₅₀ of ~25 µM. Does not affect p300/CREB binding protein-associated factor (PCAF).
  • CAS Number
    458-37-7
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₁H₂₀O₆
  • Molecular Weight
    368.38
  • Cell Permeable
    Yes
  • Purity
    ≥98%
  • Solubilities
    DMSO (25 mg/ml) or EtOH (10 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A potent antioxidant
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD00008365
  • PubChem CID
    969516
  • SMILES
    COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
  • InChi
    InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
  • InChi Key
    VFLDPWHFBUODDF-FCXRPNKRSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Curcumin, Curcuma longa ( Purity)
  • Alternative name
    Curcumin, Curcuma longa (High Purity)
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